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“成釉细胞瘤的个性化医疗时机已到?”:一种假说。

"Is it time for personalised medicine for Ameloblastoma?": A hypothesis.

作者信息

Narayan Bhaskar, Kumar Somesh, Kumar Priya, Urs Aadithya B

机构信息

Department of Oral and Maxillofacial Pathology and Microbiology, Maulana Azad Institute of Dental Sciences, New Delhi, Delhi, India.

Department of Pediatrics, Maulana Azad Medical College, New Delhi, Delhi, India.

出版信息

J Oral Maxillofac Pathol. 2023 Oct-Dec;27(4):744-745. doi: 10.4103/jomfp.jomfp_356_23. Epub 2023 Dec 20.

Abstract

Ameloblastoma is a benign odontogenic tumor that is locally destructive. The most common treatment option is surgery, which often results in disfigurement of the face. BRAF is the common gene mutation associated with its pathogenesis. Therefore, this paper hypothesizes the use of targeted drug therapy against this mutated gene.

摘要

成釉细胞瘤是一种具有局部破坏性的良性牙源性肿瘤。最常见的治疗选择是手术,这往往会导致面部毁容。BRAF是与其发病机制相关的常见基因突变。因此,本文假设使用针对这种突变基因的靶向药物治疗。

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