Mills R, Brain C
Clin Otolaryngol Allied Sci. 1985 Dec;10(6):303-6. doi: 10.1111/j.1365-2273.1985.tb00260.x.
The parents of children with secretory otitis media and the parents of healthy children attending for routine school or community medical examinations have been questioned about previous acute otitis media, aural discharge, chronic nasal symptoms and allergic disorders. Eighty-nine pairs of children, matched for age and sex, were available for analysis. There was a significantly higher incidence of acute otitis media, aural discharge and chronic nasal symptoms in the secretory otitis group (P = less than 0.001). Amongst the allergic symptoms and disorders, the only significant differences demonstrated were for drug allergy, eye itching and eye running (P = less than 0.05). The results confirm that a relationship exists between acute otitis media and secretory otitis media and also support the conventional image of the child with secretory otitis as a mouth breather with nasal symptoms. They do not lend support to the view that allergy is an important factor in the pathogenesis of secretory otitis.
对患有分泌性中耳炎儿童的父母以及参加常规学校或社区体检的健康儿童的父母，询问了他们孩子以前是否患过急性中耳炎、耳部流脓、慢性鼻部症状和过敏性疾病。八十九对年龄和性别匹配的儿童可供分析。分泌性中耳炎组急性中耳炎、耳部流脓和慢性鼻部症状的发病率明显更高（P < 0.001）。在过敏症状和疾病中，唯一显示出显著差异的是药物过敏、眼痒和流泪（P < 0.05）。结果证实急性中耳炎和分泌性中耳炎之间存在关联，也支持了分泌性中耳炎患儿有鼻部症状且用口呼吸的传统形象。但它们并不支持过敏是分泌性中耳炎发病机制中重要因素的观点。
