Centre for Neuroscience, Indian Institute of Science, Bangalore, KA, India.
Department of Neurobiology, Stanford University School of Medicine, Stanford, CA, USA.
Sci Adv. 2024 Feb 2;10(5):eadi0645. doi: 10.1126/sciadv.adi0645.
Attention can be deployed in multiple forms and facilitates behavior by influencing perceptual sensitivity and choice bias. Attention is also associated with a myriad of changes in sensory neural activity. Yet, the relationship between the behavioral components of attention and the accompanying changes in neural activity remains largely unresolved. We examined this relationship by quantifying sensitivity and bias in monkeys performing a task that dissociated eye movement responses from the focus of covert attention. Unexpectedly, bias, not sensitivity, increased at the focus of covert attention, whereas sensitivity increased at the location of planned eye movements. Furthermore, neuronal activity within visual area V4 varied robustly with bias, but not sensitivity, at the focus of covert attention. In contrast, correlated variability between neuronal pairs was lowest at the location of planned eye movements, and varied with sensitivity, but not bias. Thus, dissociable behavioral components of attention exhibit distinct neuronal signatures within the visual cortex.
注意力可以以多种形式进行部署，并通过影响感知灵敏度和选择偏差来促进行为。注意力也与感觉神经活动的无数变化有关。然而，注意力的行为成分与伴随的神经活动变化之间的关系在很大程度上仍未得到解决。我们通过量化猴子在执行一项任务时的敏感性和偏差来检查这种关系，该任务将眼球运动反应与隐蔽注意力的焦点分开。出乎意料的是，在隐蔽注意力的焦点处，偏差而不是敏感性增加，而在计划眼球运动的位置处，敏感性增加。此外，在视觉区域 V4 内的神经元活动在隐蔽注意力的焦点处与偏差而不是敏感性强烈相关，但在计划眼球运动的位置处不相关。相比之下，在计划眼球运动的位置处，神经元对之间的相关变异性最低，并且与敏感性而不是偏差相关。因此，注意力的可分离行为成分在视觉皮层中表现出不同的神经元特征。
