College of Engineering, China Agricultural University, Beijing 100083, China.
Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Int J Biol Macromol. 2024 Mar;261(Pt 2):129851. doi: 10.1016/j.ijbiomac.2024.129851. Epub 2024 Feb 1.
Pectin is a complex polysaccharide that is widely present in plant cells and has multiple physiological functions. However, most pectin exists in the form of protopectin, which has a large molecular weight and cannot be fully absorbed and utilized in the human gut to exert its effects. The significant differences in the structure of different sources of pectin also limited their application in the food and medical fields. In order to achieve greater development and utilization of pectin functions, this paper reviewed several commonly used methods for pectin modification from physical, chemical, and biological perspectives, and elaborated on the relationship between these modification methods and the structure and functional properties of pectin. At the same time, the functional characteristics of modified pectin and its application in medical health, such as regulating intestinal health, anticancer, anti-inflammatory, and drug transport, were reviewed, so as to provide a theoretical basis for targeted modification of pectin and the development of new modified pectin products.
果胶是一种广泛存在于植物细胞中的复杂多糖,具有多种生理功能。然而,大多数果胶以原果胶的形式存在,其分子量较大,不能被人体肠道完全吸收和利用,从而发挥其作用。不同来源果胶结构的显著差异也限制了它们在食品和医疗领域的应用。为了实现果胶功能的更大发展和利用,本文从物理、化学和生物学角度综述了几种常用的果胶改性方法,并详细阐述了这些改性方法与果胶结构和功能特性之间的关系。同时,综述了改性果胶的功能特性及其在医学健康领域的应用,如调节肠道健康、抗癌、抗炎和药物输送等,以期为果胶的靶向改性和新型改性果胶产品的开发提供理论依据。