Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Canada; School of Epidemiology and Public Health, Department of Medicine, University of Ottawa, Canada.
Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Canada.
J Med Imaging Radiat Sci. 2024 Jun;55(2S):S17-S25. doi: 10.1016/j.jmir.2023.12.012. Epub 2024 Feb 1.
Positron emission tomography (PET) with F-fluorodeoxyglucose (F-FDG) has recently emerged as an increasingly used alternative and supplementary imaging modality for the diagnosis of infective endocarditis. F-FDG PET/CT imaging for IE is given a Class I recommendation (level of evidence B) and is therefore recommended in cases of possible prosthetic valve IE to both detect valvular lesions, as well as confirm the diagnosis of IE. They have also given a class I recommendation (level of evidence B) for brain and whole-body F-FDG PET/CT and/or MRI imaging to detect peripheral lesions for patients with either native or prosthetic valve IE. Molecular imaging is playing an increasingly important role in the diagnosis and management of patients with IE. The important role of F-FDG PET/CT imaging has been acknowledged by recent guideline updates. These advanced imaging tests are not supplanting the role of echocardiography in the diagnostic pathway for IE. Rather, they are additional tools that are available where the diagnosis is complicated, difficult, or uncertain.
正电子发射断层扫描（PET）结合氟代脱氧葡萄糖（F-FDG）最近已成为一种越来越多被使用的替代和补充成像方式，用于感染性心内膜炎的诊断。F-FDG PET/CT 成像用于 IE 被给予 I 类推荐（证据水平 B），因此建议在可能的人工瓣膜 IE 中，用于检测瓣膜病变，以及确认 IE 的诊断。对于患有原生或人工瓣膜 IE 的患者，他们还推荐使用 I 类推荐（证据水平 B）的脑和全身 F-FDG PET/CT 和/或 MRI 成像，以检测外周病变。分子成像在 IE 患者的诊断和管理中发挥着越来越重要的作用。最近的指南更新已经承认了 F-FDG PET/CT 成像的重要作用。这些高级成像检查并未取代超声心动图在 IE 诊断途径中的作用。相反，它们是在诊断复杂、困难或不确定时可用的附加工具。
