Sekome Kganetso, Gómez-Olivé Francesc Xavier, Sherar Lauren B, Esliger Dale W, Myezwa Hellen
Department of Physiotherapy, Faculty of Health Sciences, School of Therapeutic Sciences, University of the Witwatersrand, Johannesburg, 2193, South Africa.
School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK.
Pilot Feasibility Stud. 2024 Feb 3;10(1):22. doi: 10.1186/s40814-024-01456-w.
In rural and remote South Africa, most strokes and ischaemic heart diseases are as a consequence of hypertension, which is a modifiable risk factor. The widely recommended therapeutic approaches to control hypertension are through physical activity and diet modifications. However, there is a lack of culturally sensitive community-based, lifestyle interventions to control hypertension among rural African adult populations. We designed an intervention which recommends adjusting daily routine physical activity and dietary behaviour of adults with hypertension. This study aims to evaluate the feasibility and acceptability of HYPHEN in a rural community setting.
We aim to recruit 30 adult participants with a self-report hypertension diagnosis. A one-arm, prospective design will be used to assess the feasibility and acceptability of recruitment, uptake, engagement, and completion of the 10-week intervention. Recruitment rates will be assessed at week 0. Intervention uptake, engagement, and adherence to the intervention will be assessed weekly via telephone. Blood pressure, body mass index, waist-hip ratio, urinary sodium, accelerometer-measured physical activity, and 24-h diet recall will be assessed at baseline and at 10 weeks. Qualitative semi-structured interviews will be conducted at 10 weeks to explore feasibility and acceptability.
This study offers a person-centred, sociocultural approach to hypertension control through adaptations to physical activity and dietary intake. This study will determine whether HYPHEN is feasible and acceptable and will inform changes to the protocol/focus that could be tested in a full trial.
PACTR202306662753321.
在南非农村和偏远地区，大多数中风和缺血性心脏病是由高血压引起的，而高血压是一个可改变的风险因素。广泛推荐的控制高血压的治疗方法是通过体育活动和饮食调整。然而，缺乏对非洲农村成年人群具有文化敏感性的基于社区的生活方式干预措施来控制高血压。我们设计了一种干预措施，建议调整高血压成年人的日常体育活动和饮食行为。本研究旨在评估“高血压生活方式干预及评估试验（HYPHEN）”在农村社区环境中的可行性和可接受性。
我们旨在招募30名自我报告患有高血压的成年参与者。将采用单臂前瞻性设计来评估招募、参与、参与度以及完成为期10周干预的可行性和可接受性。在第0周评估招募率。通过电话每周评估干预的参与率、参与度和依从性。在基线和第10周评估血压、体重指数、腰臀比、尿钠、加速度计测量的体育活动以及24小时饮食回忆。在第10周进行定性半结构化访谈，以探讨可行性和可接受性。
本研究通过调整体育活动和饮食摄入量，提供了一种以患者为中心、社会文化的高血压控制方法。本研究将确定“高血压生活方式干预及评估试验（HYPHEN）”是否可行和可接受，并为可在全面试验中测试的方案/重点的改变提供信息。
PACTR202306662753321。
