Center for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Harvard Center for Population and Development Studies, Harvard University, Cambridge, Massachusetts, USA.
Am J Hypertens. 2023 May 21;36(6):324-332. doi: 10.1093/ajh/hpad018.
Over half of the South African adults aged 45 years and older have hypertension but its effective management along the treatment cascade (awareness, treatment, and control) remains poorly understood.
We compared the prevalence of all stages of the hypertension treatment cascade in the rural HAALSI cohort of older adults at baseline and after four years of follow-up using household surveys and blood pressure data. Hypertension was a mean systolic blood pressure >140 mm Hg or diastolic pressure >90 mm Hg, or current use of anti-hypertension medication. Control was a mean blood pressure <140/90 mm Hg. The effects of sex and age on the treatment cascade at follow-up were assessed. Multivariate Poisson regression models were used to estimate prevalence ratios along the treatment cascade at follow-up.
Prevalence along the treatment cascade increased from baseline (B) to follow-up (F): awareness (64.4% vs. 83.6%), treatment (49.7% vs. 73.9%), and control (22.8% vs. 41.3%). At both time points, women had higher levels of awareness (B: 70.5% vs. 56.3%; F: 88.1% vs. 76.7%), treatment (B: 55.9% vs. 41.55; F: 79.9% vs. 64.7%), and control (B: 26.5% vs. 17.9%; F: 44.8% vs. 35.7%). Prevalence along the cascade increased linearly with age for everyone. Predictors of awareness included being female, elderly, or visiting a primary health clinic three times in the previous 3 months, and the latter two also predicted hypertension control.
There were significant improvements in awareness, treatment, and control of hypertension from baseline to follow-up and women fared better at all stages, at both time points.
超过一半的南非 45 岁及以上成年人患有高血压,但对其沿治疗阶梯(知晓、治疗和控制)的有效管理仍知之甚少。
我们使用家庭调查和血压数据比较了基线时和四年随访后农村 HAALSI 队列中老年成年人高血压治疗阶梯各阶段的患病率。高血压定义为平均收缩压>140mmHg 或舒张压>90mmHg,或正在使用抗高血压药物。控制定义为平均血压<140/90mmHg。评估了性别和年龄对随访时治疗阶梯的影响。使用多变量泊松回归模型估计随访时治疗阶梯的患病率比。
治疗阶梯的患病率从基线(B)到随访(F)增加:知晓率(64.4% vs. 83.6%)、治疗率(49.7% vs. 73.9%)和控制率(22.8% vs. 41.3%)。在两个时间点,女性的知晓率(B:70.5% vs. 56.3%;F:88.1% vs. 76.7%)、治疗率(B:55.9% vs. 41.55%;F:79.9% vs. 64.7%)和控制率(B:26.5% vs. 17.9%;F:44.8% vs. 35.7%)均较高。治疗阶梯的患病率随年龄呈线性增加,所有人均如此。知晓率的预测因素包括女性、年龄较大或在过去 3 个月内 3 次就诊于初级保健诊所,后两者也预测高血压控制情况。
从基线到随访,高血压的知晓率、治疗率和控制率均有显著改善,且女性在两个时间点的所有阶段均表现更好。