Urology Department, Faculty of Medicine, Lebanese University, Al Zahraa Hospital, Beirut, Lebanon.
Urology Department, Lebanese University, Beirut, Lebanon.
World J Urol. 2024 Feb 3;42(1):68. doi: 10.1007/s00345-024-04770-3.
Urinary Tract Infections (UTIs) and Genital Tract Infections (GTIs) are common yet serious health concerns. Precise diagnosis is crucial due to the potential severe consequences of misdiagnosis. This study aims to distinguish between UTIs and GTIs, highlighting the importance of accurate differentiation.
The study encompassed 294 patients, categorized into 4 groups: Group GNI (no infection, N = 57), Group GUI (urinary infection, N = 52), Group GGI (genital infection, N = 139), and Group GGUI (both infections, N = 46). Methods included patient interviews, clinical examinations, and laboratory tests such as urine and vaginal swab cultures.
The investigation revealed no significant differences in age, BMI, residency, or nationality across groups. However, socioeconomic status varied, with Group GNI having the lowest proportion of low socioeconomic status. In obstetrical characteristics, non-pregnancy rates were higher in Groups GUI and GGUI, with GGUI showing a notably higher abortion rate. Symptom analysis indicated lower symptom prevalence in Group GNI, with pain, itching, pruritus, and vaginal discharge being less frequent, suggesting a link between infection presence and symptom severity. Treatment patterns showed higher usage of ciprofloxacin, antifungals, and vaginal tablets in Groups GUI and GGUI. Laboratory findings highlighted significant Leucocyte Esterase presence and variations in WBC and RBC counts, particularly in Group GGUI.
The study emphasizes the need for advanced diagnostic techniques, especially those focusing on individual microbial patterns, to enhance UGTI diagnosis. Variations in symptom presentation and treatment across groups underline the necessity for personalized diagnostic and treatment strategies.
尿路感染（UTIs）和生殖道感染（GTIs）是常见但严重的健康问题。由于误诊可能带来严重后果，准确诊断至关重要。本研究旨在区分 UTIs 和 GTIs，强调准确区分的重要性。
该研究纳入了 294 名患者，分为 4 组：GNI 组（无感染，N=57）、GUI 组（尿路感染，N=52）、GGG 组（生殖道感染，N=139）和 GGIG 组（两种感染，N=46）。方法包括患者访谈、临床检查和实验室检查，如尿液和阴道拭子培养。
研究发现，各组间年龄、BMI、居住地点和国籍无显著差异。然而，社会经济地位存在差异，GNI 组的低收入人群比例最低。在产科特征方面，GUI 和 GGIG 组的非妊娠率较高，而 GGIG 组的流产率明显较高。症状分析表明，GNI 组的症状发生率较低，疼痛、瘙痒、瘙痒和阴道分泌物较少，提示感染存在与症状严重程度之间存在关联。治疗模式表明，GUI 和 GGIG 组更常使用环丙沙星、抗真菌药和阴道片剂。实验室结果突出了白细胞酯酶的存在以及白细胞和红细胞计数的变化，特别是在 GGIG 组。
本研究强调需要先进的诊断技术，特别是那些专注于个体微生物模式的技术，以提高 UGTI 的诊断水平。各组间症状表现和治疗方法的差异强调了制定个性化诊断和治疗策略的必要性。
