Caldarola L, Volterrani P, Lai M, Vigezzi P, Gaglia P
Ital J Surg Sci. 1985;15(4):329-33.
The correlation between estrogen (ER) and progesterone (PgR) receptor status and some clinical and pathological features was evaluated in a series of 680 breast carcinomas. ER status was significantly related to age, menopause, histological grade and vascular invasion. No relationship was found with tumor size, lymph node involvement, histotype and multicentricity. PgR status was significantly related to vascular invasion only. Despite the relationship between ER and favorable pathological features, ER-positive patients did not show a longer disease-free interval after surgery when no systemic adjuvant therapy was administered. ER status is thus of little prognostic value.
在一系列680例乳腺癌中评估了雌激素（ER）和孕激素（PgR）受体状态与一些临床和病理特征之间的相关性。ER状态与年龄、绝经状态、组织学分级和血管侵犯显著相关。未发现与肿瘤大小、淋巴结受累情况、组织学类型和多中心性有关。PgR状态仅与血管侵犯显著相关。尽管ER与良好的病理特征相关，但在未进行全身辅助治疗的情况下，ER阳性患者术后无病生存期并未延长。因此，ER状态的预后价值不大。
