Department of Urology, Glasgow Royal Infirmary, NHS Greater Glasgow and Clyde, Glasgow, UK; College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Department of Surgical Oncology, All India Institute of Medical Sciences, New Delhi, India; Department of General Surgery, Royal Albert Edward Infirmary, WWL NHS Trust, Wigan, UK.
Urology. 2024 Mar;185:100-108. doi: 10.1016/j.urology.2024.01.010. Epub 2024 Feb 1.
To synthesise the evidence comparing the incidence rates of UAS post-RARC vs Open Radical cystectomy (ORC) in adults undergoing cystectomy and to compare differential stricture rates between Extracorporeal and Intracorporeal urinary diversion (ECUD vs ICUD). The primary outcome was incidence rate of UAS post RARC vs ORC and the secondary outcome was incidence rate of UAS in RARC post ECUD vs ICUD. Review authors conducted comprehensive search for studies comparing RARC with ORC in terms of incidence of UAS. Furthermore, we conducted a secondary search for studies which compared UAS incidence comparing ECUD and ICUD. We found that RARC may have higher incidence of UAS [OR: 1.39; 95% CI 1.11-1.75; p < 0.0001]. ECUD may result in lower rate of UAS as compared to ICUD [OR: 0.74; 95% CI 0.56 to 0.98; p= 0.04].
旨在综合比较根治性膀胱切除术(RARC)后与开放性根治性膀胱切除术(ORC)后成年人上尿路症状(UAS)发生率的证据,并比较体外与体内尿流改道术(ECUD 与 ICUD)之间的差异狭窄率。主要结局是 RARC 后 UAS 发生率与 ORC 相比,次要结局是 RARC 后 ECUD 与 ICUD 相比 UAS 发生率。综述作者对比较 RARC 与 ORC 中 UAS 发生率的研究进行了全面检索。此外,我们还对比较 ECUD 和 ICUD 中 UAS 发生率的研究进行了二次检索。结果发现,RARC 可能具有更高的 UAS 发生率[OR:1.39;95%CI 1.11-1.75;p<0.0001]。与 ICUD 相比,ECUD 可能导致 UAS 发生率较低[OR:0.74;95%CI 0.56 至 0.98;p=0.04]。