From the Department of Orthopedic Surgery and Traumatology (Samargandi, Le Nail, Saad), The Regional University Hospital Centre of Tours, Tours, France, and from the Department of Orthopedic Surgery (Samargandi, Hetaimish), College of Medicine, University of Jeddah, Jeddah, Kingdom of Saudi Arabia.
Saudi Med J. 2024 Feb;45(2):194-198. doi: 10.15537/smj.2024.45.2.20230334.
Systemic cobalt-chromium (Co-Cr) toxicity following a total hip replacement is a rare complication that may sometimes lead to fatal consequences. We report a case of a 64-year-old woman, who presented with Co-Cr toxicity after revision of fractured ceramic components with metal-on-polyethylene. Systemic toxicity occurred a year after surgery and was expressed brutally with mostly central neurological symptoms. Revision surgery allowed rapid regression of all symptoms. Prosthetic revision with a metal bearing surface after a history of fracture of the ceramic bearing component should be avoided. Orthopedic surgeons and the different medical actors should be aware of this rare but serious complication to allow earlier management. Above all, multidisciplinary management is primordial to allow correct diagnosis and appropriate treatment.
全髋关节置换术后发生全身性钴铬（Co-Cr）中毒是一种罕见的并发症，有时可能导致致命后果。我们报告了一例 64 岁女性病例，该患者在因陶瓷部件断裂而进行金属对聚乙烯翻修后出现 Co-Cr 中毒。术后 1 年发生全身毒性，主要表现为中枢神经系统症状。翻修手术使所有症状迅速消退。对于陶瓷承载体部件断裂病史的患者，应避免使用金属承载体表面进行假体翻修。骨科医生和不同的医疗人员应该意识到这种罕见但严重的并发症，以便更早地进行治疗。最重要的是，多学科管理对于正确诊断和适当治疗至关重要。
