Zhang Shuxin, Xiao Jingyu, Zhong Geng, Xu Tailin, Zhang Xueji
School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen 518060, China.
Analyst. 2024 Feb 26;149(5):1381-1397. doi: 10.1039/d3an02187d.
Metal-organic frameworks (MOFs) are novel inorganic-organic hybridized crystals with a wide range of applications. In the last twenty years, fluorescence sensing based on MOFs has attracted much attention. MOFs can exhibit luminescence from metal nodes, ligands or introduced guests, which provides an excellent fluorescence response in sensing. However, single-signal emitting MOFs are susceptible to interference from concentration, environment, and excitation intensity, resulting in poor accuracy. To overcome the shortcomings, dual-emission MOF-based ratiometric fluorescence sensors have been proposed and rapidly developed. In this review, we first introduce the luminescence mechanisms, synthetic methods, and detection mechanisms of dual-emission MOFs, highlight the strategies for constructing ratiometric fluorescence sensors based on dual-emission MOFs, and classify them into three categories: intrinsic dual-emission and single-emission MOFs with luminescent guests, and non-emission MOFs with other luminescent materials. Then, we summarize the recent advances in dual-emission MOF-based ratiometric fluorescence sensors in various analytical industries. Finally, we discuss the current challenges and prospects for the future development of these sensors.
金属有机框架材料（MOFs）是一类具有广泛应用的新型无机-有机杂化晶体。在过去二十年中，基于MOFs的荧光传感受到了广泛关注。MOFs可表现出源于金属节点、配体或引入客体的发光，这为传感提供了出色的荧光响应。然而，单信号发射的MOFs易受浓度、环境和激发强度的干扰，导致准确性较差。为克服这些缺点，基于双发射MOFs的比率荧光传感器被提出并迅速发展。在本综述中，我们首先介绍双发射MOFs的发光机制、合成方法和检测机制，重点阐述基于双发射MOFs构建比率荧光传感器的策略，并将其分为三类：本征双发射和带有发光客体的单发射MOFs，以及与其他发光材料结合的非发射MOFs。然后，我们总结了基于双发射MOFs的比率荧光传感器在各分析领域的最新进展。最后，我们讨论了这些传感器当前面临的挑战以及未来发展前景。
