Hakim Wissam Saleh, Aljanabi Ali Saleh
Department of Surgery, College of Medicine, University of Al-Qadisiyah, Iraq.
J Med Life. 2023 Oct;16(10):1499-1502. doi: 10.25122/jml-2023-0190.
A series of birth defects known as neural tube defects (NTDs) appear when the neural tube fails to fully or partially close during fetal development. In nations without folic acid supplementation, their incidence ranges from 0.5 to 2 per 1,000 births. The purpose of our study is to estimate the prevalence of NTDs and define the workup for newborn infants with an open neural tube in Al-Qadissiyah, Iraq. This 18-year descriptive retrospective analysis included all babies with NTD diagnoses at the Maternity and Child Teaching Hospital in Al-Qadissiyah Governorate, Iraq. Over the research period, 187 cases of NTDs were evaluated. NTDs presented a male predominance and an incidence rate of 9.4 per 1,000 births, with spina bifida (67.9%), encephalocele (24.02%), and anencephaly (8.02%) being the most prevalent defects. The typical gestational age was 36±5, whereas the typical maternal age was 30±5. It should be noted that 29.9% of women did not take folic acid supplements during the first trimester, while one-third of moms did not benefit from medical supervision during pregnancy. In 65.2% of instances, an antenatal diagnosis was made, and cesarean section was the mode of delivery in 87,8% of cases. Other than that, 64.7% of women lived in low socioeconomic conditions, and 67.9% were from rural areas. The relevance of reinforcing and maximizing folic acid measures throughout the periconceptional phase is emphasized by the fact that NTDs require high intensity and advanced care.
一系列被称为神经管缺陷(NTDs)的出生缺陷,是在胎儿发育过程中神经管未能完全或部分闭合时出现的。在没有叶酸补充剂的国家,其发病率为每1000例出生中有0.5至2例。我们研究的目的是估计伊拉克卡迪西亚省神经管缺陷的患病率,并确定患有开放性神经管的新生儿的检查方法。这项为期18年的描述性回顾性分析纳入了伊拉克卡迪西亚省妇幼教学医院所有被诊断为神经管缺陷的婴儿。在研究期间,对187例神经管缺陷病例进行了评估。神经管缺陷以男性居多,发病率为每1000例出生中有9.4例,其中脊柱裂(67.9%)、脑膨出(24.02%)和无脑儿(8.02%)是最常见的缺陷。典型的孕周为36±5周,而典型的产妇年龄为30±5岁。需要注意的是,29.9%的女性在孕早期未服用叶酸补充剂,而三分之一的母亲在孕期未接受医疗监护。在65.2%的情况下进行了产前诊断,87.8%的病例以剖宫产方式分娩。除此之外,64.7%的女性生活在社会经济条件较差的环境中,67.9%来自农村地区。神经管缺陷需要高强度和先进的护理,这一事实强调了在整个受孕前阶段加强和最大化叶酸措施的重要性。