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一名结核性中耳炎患者合并感染 。 (原文中“Co-infection with”后面缺少具体内容)

Co-infection with in a patient with tuberculous otitis media.

作者信息

Hioki Tatsuya, Soejima Kazuaki, Goto Yuki, Sugiura Makoto, Umemura Takumi, Ishihara Yoshimi, Mutoh Yoshikazu, Sakanashi Daisuke, Mikamo Hiroshige

机构信息

Department of Clinical Laboratory, Tosei General Hospital, 160 Nishioiwake-cho, Seto, Aichi, 489-8642, Japan.

Department of Respiratory Medicine and Allergy, Tosei General Hospital, 160 Nishioiwake-cho, Seto, Aichi, 489-8642, Japan.

出版信息

J Otol. 2024 Jan;19(1):1-4. doi: 10.1016/j.joto.2023.10.001. Epub 2023 Oct 12.

DOI:10.1016/j.joto.2023.10.001
PMID:38313762
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10837539/
Abstract

Tuberculous otitis media (TOM) is a rare manifestation caused by with low incidence rates among extrapulmonary tuberculosis cases. Diagnosis is often delayed because of the presence of several clinical manifestations and the high prevalence of secondary bacterial infections. Few reports have attributed secondary bacterial infections in patients with TOM to commensal . Thus, understanding the pathogenic mechanisms and clinical features of commensal is important, considering its recent presentation as an infection-causing pathogen. is a commensal inhabitant in humans and is generally considered non-pathogenic but can cause infection in rare cases. Here, we report an atypical secondary infection caused by in an 81-year-old woman with TOM being treated for pulmonary tuberculosis. Direct purulent otorrhea smear microscopy revealed no acid-fast bacilli using Ziehl-Neelsen staining, whereas the phagocytosis of gram-negative cocci by white blood cells was confirmed using Gram staining. Otorrhea culture revealed the growth of . Subsequently, infection in the otorrhea was identified using a culture-based method. Vigilance is critical for the early detection of TOM to prevent further complications. This report raises awareness regarding TOM and provides insight into the pathogenicity of in otitis media.

摘要

结核性中耳炎(TOM)是肺外结核病例中由[未提及的病原体]引起的一种罕见表现,发病率较低。由于存在多种临床表现以及继发性细菌感染的高患病率,诊断往往会延迟。很少有报告将TOM患者的继发性细菌感染归因于共生菌[未提及的共生菌名称]。因此,考虑到其最近作为一种致病病原体的出现,了解共生菌[未提及的共生菌名称]的致病机制和临床特征很重要。[未提及的共生菌名称]是人类的共生菌,通常被认为是非致病性的,但在罕见情况下可引起感染。在这里,我们报告了一例81岁患有TOM且正在接受肺结核治疗的女性患者由[未提及的共生菌名称]引起的非典型继发性感染。直接脓性耳漏涂片显微镜检查使用齐-尼氏染色未发现抗酸杆菌,而使用革兰氏染色证实白细胞对革兰氏阴性球菌有吞噬作用。耳漏培养显示[未提及的共生菌名称]生长。随后,使用基于培养的方法在耳漏中鉴定出[未提及的共生菌名称]感染。警惕对于早期发现TOM以预防进一步并发症至关重要。本报告提高了对TOM的认识,并提供了对[未提及的共生菌名称]在中耳炎中的致病性的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c734/10837539/b6e916414caf/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c734/10837539/b6e916414caf/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c734/10837539/b6e916414caf/gr1.jpg

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