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2000年至2021年巴西糖尿病死亡率趋势:深入的连接点分析

Diabetes Mellitus Mortality Trends in Brazil From 2000 to 2021: An In-Depth Joinpoint Analysis.

作者信息

McBenedict Billy, Hauwanga Wilhelmina, Lizarazo Javier F, Djeagou Albine, Akram Ifrah

机构信息

Medicine, Hospital Universitário Antônio Pedro, Niterói, BRA.

Family Medicine, Faculty of Medicine, Federal University of the State of Rio de Janeiro, Rio de Janeiro, BRA.

出版信息

Cureus. 2024 Jan 4;16(1):e51632. doi: 10.7759/cureus.51632. eCollection 2024 Jan.

DOI:10.7759/cureus.51632
PMID:38313987
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10837682/
Abstract

Diabetes mellitus (DM) is a public health concern in Brazil, with deleterious effects on quality of life and increasing mortality rates. The prevalence of diabetes in Brazil is on the rise, and it is imperative to understand its effects on mortality rates in the last two decades in order to effectively mitigate the detrimental impact of diabetes on public health. This study aims to analyze mortality trends related to diabetes in Brazil from 2000 to 2021, encompassing both type 1 and type 2 diabetes, across sex and various age cohorts. Using joinpoint regression analysis, temporal trends in Brazil were assessed, while also incorporating findings from previous studies and considering potential influencing factors, such as government initiatives and cuts in healthcare investment. The study revealed a general upward trend in mortality rates associated with DM1 and DM2 over the study period, in both males and females, with men showing a higher AAPC (average annual percent change), which translated into significantly increased mortality difference at the end of the study. Additionally, it revealed elevated mortality values for extreme age groups in the age cohorts studied, with the exception of middle-aged cohort groups in DM2, which showed an expected higher APC (annual percent change), considering the age of highest incidence of DM2 in those age groups. This comprehensive analysis provides critical insights into the escalating impact of diabetes on mortality rates in Brazil and highlights the urgent need for healthcare strategies. It is expected that the increased prevalence of diabetes in the Brazilian population adds an additional economic burden to healthcare expenditure by the Brazilian government, further worsening the health disparities among different social groups. Unless several political decisions to reduce healthcare expenditure are reversed, greater difficulties in accessing treatments will be detrimental for vulnerable social groups in Brazil. By understanding the nuanced patterns of diabetes-related mortality, healthcare providers and policymakers can allocate resources effectively and implement tailored interventions to better address diabetes in Brazil.

摘要

糖尿病(DM)是巴西的一个公共卫生问题,对生活质量有有害影响,且死亡率不断上升。巴西糖尿病的患病率正在上升,了解其在过去二十年对死亡率的影响对于有效减轻糖尿病对公共卫生的不利影响至关重要。本研究旨在分析2000年至2021年巴西与糖尿病相关的死亡率趋势,涵盖1型和2型糖尿病,涉及不同性别和各个年龄组。使用连接点回归分析评估了巴西的时间趋势,同时纳入了先前研究的结果,并考虑了潜在影响因素,如政府举措和医疗保健投资削减。研究显示,在研究期间,1型糖尿病(DM1)和2型糖尿病(DM2)相关的死亡率在男性和女性中总体呈上升趋势,男性的平均年度百分比变化(AAPC)更高,这导致在研究结束时死亡率差异显著增加。此外,研究还揭示了在所研究年龄组中极端年龄组的死亡率较高,但2型糖尿病中年年龄组除外,考虑到这些年龄组中2型糖尿病的最高发病率年龄,该组显示出预期较高的年度百分比变化(APC)。这一全面分析为糖尿病对巴西死亡率不断升级的影响提供了关键见解,并突出了医疗保健策略的迫切需求。预计巴西人口中糖尿病患病率的增加会给巴西政府的医疗保健支出增加额外的经济负担,进一步加剧不同社会群体之间的健康差距。除非扭转几项削减医疗保健支出的政治决定,否则获得治疗的更大困难将对巴西的弱势群体不利。通过了解糖尿病相关死亡率的细微模式,医疗保健提供者和政策制定者可以有效地分配资源,并实施针对性的干预措施,以更好地应对巴西的糖尿病问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a893/10837682/17c32ea5c1d0/cureus-0016-00000051632-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a893/10837682/cdfb881dab23/cureus-0016-00000051632-i01.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a893/10837682/17c32ea5c1d0/cureus-0016-00000051632-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a893/10837682/cdfb881dab23/cureus-0016-00000051632-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a893/10837682/91bd9f96bada/cureus-0016-00000051632-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a893/10837682/997d4cb22e53/cureus-0016-00000051632-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a893/10837682/ea0a7f53769d/cureus-0016-00000051632-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a893/10837682/9340730b195f/cureus-0016-00000051632-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a893/10837682/17c32ea5c1d0/cureus-0016-00000051632-i06.jpg

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