Institute of Population Research, Peking University/PKU-APEC Health Science Academy, Beijing, China.
Institute of Child and Adolescent Health, School of Public Health, Peking University Health Science Center, Beijing, China.
Front Endocrinol (Lausanne). 2022 Jan 17;12:777654. doi: 10.3389/fendo.2021.777654. eCollection 2021.
Diabetes mellitus is emerging as an epidemic worldwide, and the incidence and prevalence of diabetes have drastically changed in China over the past 30 years, but data on its mortality rate are scarce. This study aimed to analyze the time trends of mortality rates among patients with diabetes in the rural and urban population in China between 1987 and 2019.
The research data come from China's annual report on national health statistics and the Chinese Health Statistics Yearbook. Age-standardized mortality rates were calculated by using the direct method based on the World Standard Population from the WHO. Joinpoint regression analysis was employed to estimate the annual percent change and average annual percentage changes of mortality rates of diabetes mellitus.
An overall trend for increment in diabetes mortality was observed. The crude mortality rates and age-standardized mortality rates of diabetes for urban and rural residents in China showed a significant increasing trend between 1987 and 2019. Mortality due to diabetes in urban areas has been higher than in rural areas for 30 years. However, due to the rapid increase of rural diabetes mortality in the past decade, the gap between the two gradually narrowed. The age-standardized mortality rates of diabetes increased by about 38.5% in urban areas and 254.9% in rural areas over the whole study period. In addition, the age-standardized mortality rate of females with diabetes was higher than that of males, but this pattern began to change in urban areas in 2012. Finally, the age-standardized mortality rates in the elderly population in China are higher with a faster growth rate, especially in rural areas.
The mortality rate of diabetes is on the rise in China. The rapid growth of the mortality rate of diabetes in rural areas leads to the reduction of the urban-rural gap. Male mortality rates in urban areas have surpassed those of women. At the same time, the mortality rate of diabetes showed obvious elder-group orientation. As China's population ages, the burden of death and disability caused by diabetes and its complications will continue to increase. These results indicate that diabetes has become a significant public health problem in China. Such an effect increases the demand for strategies aimed at the prevention and treatment of diabetes mellitus. In addition to the prevention and intervention of diabetes in high-risk groups, it is also necessary to establish diabetes screening networks to identify patients with mild symptoms. Early detection and timely intervention can effectively reduce the incidence and mortality of diabetes.
糖尿病在全球范围内呈流行趋势,中国过去 30 年糖尿病的发病率和患病率发生了巨大变化,但死亡率数据却很少。本研究旨在分析 1987 年至 2019 年中国城乡人群糖尿病死亡率的时间趋势。
研究数据来自中国国家卫生统计年度报告和《中国卫生统计年鉴》。采用世界卫生组织(WHO)的世界标准人口直接法计算年龄标化死亡率。采用 Joinpoint 回归分析估计糖尿病死亡率的年变化百分比和平均年变化百分比。
观察到糖尿病死亡率总体呈上升趋势。中国城乡居民糖尿病的粗死亡率和年龄标化死亡率在 1987 年至 2019 年期间呈显著上升趋势。30 年来,城市地区糖尿病死亡率一直高于农村地区。然而,由于过去 10 年农村糖尿病死亡率的快速上升,两者之间的差距逐渐缩小。整个研究期间,城市地区糖尿病的年龄标化死亡率增加了约 38.5%,农村地区增加了 254.9%。此外,女性糖尿病的年龄标化死亡率高于男性,但这种模式在 2012 年开始在城市地区发生变化。最后,中国老年人群的年龄标化死亡率较高,增长率较快,尤其是在农村地区。
中国的糖尿病死亡率呈上升趋势。农村地区糖尿病死亡率的快速增长导致城乡差距缩小。城市地区男性死亡率已超过女性。同时,糖尿病死亡率呈现明显的老年化趋势。随着中国人口老龄化,糖尿病及其并发症导致的死亡和残疾负担将继续增加。这些结果表明,糖尿病已成为中国的一个重大公共卫生问题。这种影响增加了对预防和治疗糖尿病的策略的需求。除了对高危人群的糖尿病预防和干预外,还需要建立糖尿病筛查网络,以识别轻度症状的患者。早期发现和及时干预可以有效降低糖尿病的发病率和死亡率。