Chen Xiao, Xu Chunmei, Wu Yafei, Zhao Lei
State Key Laboratory of Oral Diseases and National Center for Stomatology and National Clinical Research Center for Oral Diseases and Department of Periodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
J Clin Periodontol. 2024 May;51(5):631-651. doi: 10.1111/jcpe.13951. Epub 2024 Feb 5.
This systematic review and meta-analysis aimed to determine the survival of periodontally treated molars during maintenance care and identify the risk factors associated with molar loss among patients with periodontitis who received professional periodontal therapy and maintenance.
Longitudinal studies with a minimum follow-up duration of 5 years published until 28 August 2023 were retrieved from the following databases: the Cochrane Library, Embase, MEDLINE and Web of Science. All included studies reported data on molar retention. Meta-analysis was performed using Review Manager 5.4. A modified version of the Newcastle-Ottawa Scale was used to evaluate the study quality. Statistical results of analyses of the overall survival rate and molar loss are presented as estimated standardized mean differences, whereas the results of the analyses of risk factors are presented as risk ratios with 95% confidence intervals (95% CIs).
From among the 1323 potentially eligible reports, 41 studies (5584 patients, 29,908 molars retained at the beginning of maintenance therapy, mean follow-up duration of 14.7 years) were included. The pooled survival rate of the molars during maintenance therapy was 82% (95% CI: 80%-84%). The average loss of molars was 0.05 per patient per year (95% CI: 0.04-0.06) among the patients receiving long-term periodontal maintenance (PM) therapy. Fifteen factors were examined in this meta-analysis. Six patient-related factors (older age, lack of compliance, smoking, bruxism, diabetes and lack of private insurance) and five tooth-related factors (maxillary location, high probing pocket depth, furcation involvement, higher mobility and lack of pulpal vitality) were identified as risk factors for molar loss during maintenance therapy.
The findings of the present study suggest that the long-term retention of periodontally compromised molars can be achieved. The average number of molars lost per decade was <1 among the patients receiving long-term PM therapy. Older age, noncompliance, smoking, bruxism, diabetes, lack of private insurance coverage, maxillary location, furcation involvement, higher mobility, increase in the probing pocket depth and loss of pulpal vitality are strong risk factors for the long-term prognosis of molars.
本系统评价和荟萃分析旨在确定牙周治疗后磨牙在维护期的存留情况,并识别在接受专业牙周治疗和维护的牙周炎患者中与磨牙缺失相关的危险因素。
从以下数据库检索截至2023年8月28日发表的随访时间至少为5年的纵向研究:Cochrane图书馆、Embase、MEDLINE和Web of Science。所有纳入研究均报告了磨牙存留的数据。使用Review Manager 5.4进行荟萃分析。采用纽卡斯尔-渥太华量表的修订版评估研究质量。总体生存率和磨牙缺失分析的统计结果以估计的标准化平均差表示,而危险因素分析的结果以95%置信区间(95%CI)的风险比表示。
在1323篇潜在合格报告中,纳入了41项研究(5584例患者,维护治疗开始时保留29908颗磨牙,平均随访时间14.7年)。维护治疗期间磨牙的合并存留率为82%(95%CI:80%-84%)。在接受长期牙周维护(PM)治疗的患者中,平均每人每年磨牙缺失数为0.05颗(95%CI:0.04-0.06)。本荟萃分析研究了15个因素。确定了6个与患者相关的因素(年龄较大、依从性差、吸烟、磨牙症、糖尿病和缺乏私人保险)和5个与牙齿相关的因素(上颌位置、探诊深度深、根分叉病变、松动度增加和牙髓活力丧失)为维护治疗期间磨牙缺失的危险因素。
本研究结果表明,牙周受损磨牙可实现长期存留。在接受长期PM治疗的患者中,每十年磨牙缺失的平均数量<1颗。年龄较大、不依从、吸烟、磨牙症、糖尿病、缺乏私人保险覆盖、上颌位置、根分叉病变、松动度增加、探诊深度增加和牙髓活力丧失是磨牙长期预后的强危险因素。