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魔芋葡甘聚糖基递药系统的构建与应用进展。

Advances in the construction and application of konjac glucomannan-based delivery systems.

机构信息

College of Food Science, Fujian Agriculture and Forestry University, 350000, China.

School of Food Science and Technology, Jiangnan University, 214122, China.

出版信息

Int J Biol Macromol. 2024 Mar;262(Pt 1):129940. doi: 10.1016/j.ijbiomac.2024.129940. Epub 2024 Feb 5.

DOI:10.1016/j.ijbiomac.2024.129940
PMID:38320637
Abstract

Konjac glucomannan (KGM) has been widely used to deliver bioactive components due to its naturalness, non-toxicity, excellent biodegradability, biocompatibility, and other characteristics. This review presents an overview of konjac glucomannan as a matrix, and the types of konjac glucomannan-based delivery systems (such as hydrogels, food packaging films, microencapsulation, emulsions, nanomicelles) and their construction methods are introduced in detail. Furthermore, taking polyphenol compounds, probiotics, flavor substances, fatty acids, and other components as representatives, the applied research progress of konjac glucomannan-based delivery systems in food are summarized. Finally, the prospects for research directions in konjac glucomannan-based delivery systems are examined, thereby providing a theoretical basis for expanding the application of konjac glucomannan in other industries, such as food and medicine.

摘要

魔芋葡甘聚糖(KGM)由于其天然性、无毒、优良的生物降解性、生物相容性等特点,已被广泛用于输送生物活性成分。本综述概述了魔芋葡甘聚糖作为基质,以及基于魔芋葡甘聚糖的输送系统(如水凝胶、食品包装薄膜、微胶囊、乳液、纳米胶束)的类型及其构建方法。此外,以多酚化合物、益生菌、风味物质、脂肪酸等成分为代表,总结了基于魔芋葡甘聚糖的输送系统在食品中的应用研究进展。最后,考察了基于魔芋葡甘聚糖的输送系统的研究方向,为扩大魔芋葡甘聚糖在食品等其他行业的应用提供了理论依据。

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Advances in the construction and application of konjac glucomannan-based delivery systems.魔芋葡甘聚糖基递药系统的构建与应用进展。
Int J Biol Macromol. 2024 Mar;262(Pt 1):129940. doi: 10.1016/j.ijbiomac.2024.129940. Epub 2024 Feb 5.
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Deacetylated Konjac Glucomannan Is Less Effective in Reducing Dietary-Induced Hyperlipidemia and Hepatic Steatosis in C57BL/6 Mice.去乙酰化魔芋葡甘露聚糖降低 C57BL/6 小鼠饮食诱导的高脂血症和肝脂肪变性的效果较差。
J Agric Food Chem. 2017 Mar 1;65(8):1556-1565. doi: 10.1021/acs.jafc.6b05320. Epub 2017 Feb 17.

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The Effect of SHY130 and Konjac Glucomannan on the Physicochemical, Antioxidant, and Sensory Properties of Stirred Yogurt.
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