Department of Chemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara 390 002, India.
Department of Microbiology and Biotechnology Centre, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara 390 002, India.
Int J Biol Macromol. 2024 Mar;262(Pt 1):129968. doi: 10.1016/j.ijbiomac.2024.129968. Epub 2024 Feb 4.
Chitosan is a versatile biocompatible polysaccharide which has attracted great attention for gel synthesis. Its reducing character is specifically exploited for nanoparticle synthesis via green approach. A silver nanocomposite synthesized using this gel, with a novel gelling agent 2,4,6-trihydroxy benzaldehyde, was found to be a promising candidate for several applications including anti-bacterial, anti-biofilm and anti-oxidant activity as well as catalysis. The nanocomposite was well characterized using various spectroscopic and microscopic techniques such as IR, TGA, XRD, XPS, SEM and TEM. The nanocomposite exhibited high bactericidal activity against both S. aureus and E. coli. Further, it was evaluated for anti-biofilm forming property and its potency as antioxidant agent. The nanocomposite served as a catalyst for degradation of Methyl Orange and Rhodamine B at high concentrations (in the range of mM) with a catalytic efficiency of 98.58 % and 99.56 % within 3 min and 5 min respectively.
壳聚糖是一种多功能的生物相容性多糖，因其可用于凝胶合成而备受关注。其还原特性特别适用于通过绿色方法合成纳米粒子。使用这种凝胶合成的银纳米复合材料，采用了一种新型的凝胶剂 2,4,6-三羟基苯甲醛，被发现是几种应用的有前途的候选材料，包括抗菌、抗生物膜和抗氧化活性以及催化活性。该纳米复合材料使用各种光谱和显微镜技术进行了很好的表征，例如 IR、TGA、XRD、XPS、SEM 和 TEM。纳米复合材料对金黄色葡萄球菌和大肠杆菌均表现出很高的杀菌活性。此外，还评估了其抗生物膜形成特性和抗氧化剂性能。该纳米复合材料在高浓度（mM 范围内）下作为甲基橙和罗丹明 B 的降解催化剂，在 3 分钟和 5 分钟内的催化效率分别为 98.58%和 99.56%。
