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1
Advanced thymic carcinoma with a hepatic metastasis treated with chemotherapy and staged resection.化疗联合分期切除术治疗伴肝转移的高级别胸腺癌。
BMJ Case Rep. 2024 Feb 6;17(2):e258431. doi: 10.1136/bcr-2023-258431.
2
Successful multimodal treatment in a patient with thymoma accompanied by hepatic metastasis.胸腺瘤伴肝转移患者的成功多模式治疗。
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Paclitaxel and cisplatin with concurrent radiotherapy followed by surgery in locally advanced thymic carcinoma.紫杉醇和顺铂同步放疗后手术治疗局部晚期胸腺癌。
Anticancer Res. 2007 May-Jun;27(3B):1601-4.
4
[A case of non-resectable thymoma which responded to the administration of adriamycin, vindesine and 5-FU].[一例对阿霉素、长春地辛和5-氟尿嘧啶治疗有效的不可切除胸腺瘤病例]
Gan To Kagaku Ryoho. 1986 Dec;13(12):3532-4.
5
Thymoma: current medical and surgical management.胸腺瘤：当前的医学与外科治疗
Semin Neurol. 2004 Mar;24(1):63-73. doi: 10.1055/s-2004-829588.
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Clinical Outcomes of Up-front Surgery Versus Surgery After Induction Chemotherapy for Thymoma and Thymic Carcinoma: A Retrospective Study.胸腺瘤和胸腺癌新辅助化疗后与直接手术的临床结局比较：一项回顾性研究。
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[Malignant thymoma with myasthenia gravis and hepatic metastasis. Report of a case and review of the literature].[恶性胸腺瘤伴重症肌无力及肝转移。1例报告并文献复习]
G E N. 1990 Jul-Sep;44(3):227-32.
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Predictors of survival in patients with locally advanced thymoma and thymic carcinoma (Masaoka stages III and IVa).局部晚期胸腺瘤和胸腺癌（Masaoka 分期 III 和 IVa）患者的生存预测因素。
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本文引用的文献

1
The role of surgery in advanced thymic tumors: A retrospective cohort study.手术在晚期胸腺瘤中的作用：一项回顾性队列研究。
Front Oncol. 2023 Jan 10;12:1073641. doi: 10.3389/fonc.2022.1073641. eCollection 2022.
2
Surgical, Radiation, and Systemic Treatments of Patients With Thymic Epithelial Tumors: A Systematic Review.胸腺上皮肿瘤患者的手术、放疗及全身治疗：一项系统评价
J Thorac Oncol. 2023 Mar;18(3):299-312. doi: 10.1016/j.jtho.2022.10.016. Epub 2022 Nov 4.
3
Is hepatic resection justified for non-colorectal non-neuroendocrine liver metastases? A systematic review and meta-analysis.对于非结直肠癌非神经内分泌性肝转移患者，肝切除术是否合理？一项系统评价与Meta分析。
Surgeon. 2023 Jun;21(3):160-172. doi: 10.1016/j.surge.2022.05.003. Epub 2022 Jun 17.
4
Thymic Carcinomas-A Concise Multidisciplinary Update on Recent Developments From the Thymic Carcinoma Working Group of the International Thymic Malignancy Interest Group.胸腺癌——国际胸腺癌兴趣小组胸腺癌工作组对近期进展的简要多学科更新。
J Thorac Oncol. 2022 May;17(5):637-650. doi: 10.1016/j.jtho.2022.01.021. Epub 2022 Feb 25.
5
Surgery in Masaoka stage IV thymic carcinoma: a propensity-matched study based on the SEER database.Masaoka Ⅳ期胸腺癌的手术治疗：基于监测、流行病学与结果（SEER）数据库的倾向匹配研究
J Thorac Dis. 2020 Mar;12(3):659-671. doi: 10.21037/jtd.2019.12.111.
6
Successful treatment of combined thymic epithelial tumor with hepatic metastasis: a long disease-free survival case.成功治疗合并肝转移的胸腺癌：一例无病生存长的病例。
Gen Thorac Cardiovasc Surg. 2020 Dec;68(12):1551-1554. doi: 10.1007/s11748-020-01333-2. Epub 2020 Mar 11.
7
Thymic basaloid carcinoma: a rare clinical entity.胸腺基底细胞癌：一种罕见的临床实体。
BMJ Case Rep. 2019 Nov 28;12(11):e231980. doi: 10.1136/bcr-2019-231980.
8
Thymoma and thymic carcinomas.胸腺瘤和胸腺癌。
Crit Rev Oncol Hematol. 2016 Mar;99:332-50. doi: 10.1016/j.critrevonc.2016.01.012. Epub 2016 Jan 19.
9
Thymic epithelial tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.胸腺上皮肿瘤：ESMO诊断、治疗及随访临床实践指南
Ann Oncol. 2015 Sep;26 Suppl 5:v40-55. doi: 10.1093/annonc/mdv277.
10
Epidemiology of thymoma and associated malignancies.胸腺瘤及相关恶性肿瘤的流行病学。
J Thorac Oncol. 2010 Oct;5(10 Suppl 4):S260-5. doi: 10.1097/JTO.0b013e3181f1f62d.

化疗联合分期切除术治疗伴肝转移的高级别胸腺癌。

Advanced thymic carcinoma with a hepatic metastasis treated with chemotherapy and staged resection.

机构信息

Department of General Surgery, Royal Perth Hospital, Perth, Western Australia, Australia

Department of General Surgery, Royal Perth Hospital, Perth, Western Australia, Australia.

出版信息

BMJ Case Rep. 2024 Feb 6;17(2):e258431. doi: 10.1136/bcr-2023-258431.

DOI:10.1136/bcr-2023-258431
PMID:38320822
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10860030/
Abstract

Thymic carcinoma is rare, with resulting treatment of patients with extrathoracic metastasis being on a case-by-case basis. We describe the management of a woman in her 70s with an incidentally discovered cystic hepatic lesion with confirmation of a solitary extrathoracic metastasis from a synchronous primary thymic carcinoma. Following chemotherapy and staged resection of the metastasis and the primary tumour, the patient remained free of disease on radiological surveillance 6 months postoperatively.

摘要

胸腺癌罕见，伴胸外转移的患者的治疗需根据具体情况而定。我们描述了一位 70 多岁女性的治疗经过，她因偶然发现的肝囊性病变而行进一步检查，证实存在源自同步原发性胸腺癌的单发胸外转移。该患者接受了化疗，并分期切除了转移灶和原发性肿瘤，术后 6 个月影像学监测未见疾病复发。