Michel D, Vial C, Antoine J C, Laurent B, Portafaix M, Trillet M
Rev Neurol (Paris). 1985;141(12):786-92.
Presenting symptoms in 4 patients with acute benign cerebral angiopathy were headaches over several days, with a transient neurologic disorder in two cases. Angiography showed diffuse and segmental distal narrowing alternating with dilatations. In one patient, the radiologic anomalies persisted to a milder degree in the same region 2 months later, while the reduced cerebral blood flow failed to return to normal. The pathophysiology of this syndrome would appear to result initially of vasospasm in particularly reactive subjects, especially young women. Its cause appears to vary from one case to another: post-partum disorders, infection or inflammation, meningeal hemorrhage, paroxysmal hypertension. Adjuvant factors could be unusual effort, medication or a migraine context. In spite of this pathogenetic uncertainty this angiopathy in usually considered as an isolated, benign and non-relapsing disease.
4例急性良性脑血管病患者的症状表现为持续数天的头痛，其中2例伴有短暂性神经功能障碍。血管造影显示弥漫性和节段性远端狭窄与扩张交替出现。1例患者在2个月后同一区域的放射学异常仍持续存在，但程度较轻，而脑血流量减少未能恢复正常。该综合征的病理生理学最初似乎是由于血管痉挛，特别是在反应性较强的个体中，尤其是年轻女性。其病因似乎因病例而异：产后疾病、感染或炎症、脑膜出血、阵发性高血压。辅助因素可能是异常用力、药物或偏头痛背景。尽管这种发病机制尚不确定，但这种脑血管病通常被认为是一种孤立的、良性的且不复发的疾病。
