Zhong Chaofang, Hu Gang, Hu Cong, Xu Chaohao, Zhang Zhonghua, Ning Kang
Key Laboratory of Wildlife Evolution and Conservation in Mountain Ecosystem of Guangxi, College of Environmental and Life Sciences, Nanning Normal University, Nanning 530001, China.
Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular-imaging, Department of Bioinformatics and Systems Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.
iScience. 2024 Jan 18;27(2):108948. doi: 10.1016/j.isci.2024.108948. eCollection 2024 Feb 16.
is a genus of nitrogen-fixing bacteria, with some species producing nodules in leguminous plants. Investigations into have recently revealed its substantial genetic resources and agricultural benefits, but a comprehensive survey of its genetic diversity and functional properties is lacking. Using a panel of various strains (N = 278), this study performed a comparative genomics analysis to anticipate genes linked with symbiotic nitrogen fixation. 's pan-genome consisted of 84,078 gene families, containing 824 core genes and 42,409 accessory genes. Core genes were mainly involved in crucial cell processes, while accessory genes served diverse functions, including nitrogen fixation and nodulation. Three distinct genetic profiles were identified based on the presence/absence of gene clusters related to nodulation, nitrogen fixation, and secretion systems. Most strains from soil and non-leguminous plants lacked major / genes and were evolutionarily more closely related. These findings shed light on 's genetic features for symbiotic nitrogen fixation.
是一类固氮细菌，一些物种能在豆科植物中形成根瘤。对[该细菌名称]的研究最近揭示了其丰富的遗传资源和农业益处，但缺乏对其遗传多样性和功能特性的全面调查。本研究使用一组不同的菌株（N = 278）进行了比较基因组学分析，以预测与共生固氮相关的基因。[该细菌名称]的泛基因组由84,078个基因家族组成，包含824个核心基因和42,409个辅助基因。核心基因主要参与关键的细胞过程，而辅助基因具有多种功能，包括固氮和结瘤。根据与结瘤、固氮和分泌系统相关的基因簇的存在与否，鉴定出三种不同的遗传图谱。大多数来自土壤和非豆科植物的[该细菌名称]菌株缺乏主要的[相关基因名称]基因，并且在进化上关系更密切。这些发现揭示了[该细菌名称]共生固氮的遗传特征。
