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体外心肺复苏程序在院外心脏骤停中的实施:两家县医院的又一个故事。

Implementation of Extracorporeal CPR Programs for Out-of-Hospital Cardiac Arrest: Another Tale of Two County Hospitals.

机构信息

Department of Emergency Medicine, University of Washington, Seattle, WA; Trauma & ECLS Programs, Harborview Medical Center, University of Washington, Seattle, WA.

Department of Emergency Medicine, Hennepin Healthcare, Minneapolis, MN.

出版信息

Ann Emerg Med. 2024 Nov;84(5):560-569. doi: 10.1016/j.annemergmed.2024.01.005. Epub 2024 Feb 6.

DOI:10.1016/j.annemergmed.2024.01.005
PMID:38323952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11803576/
Abstract

Extracorporeal cardiopulmonary resuscitation (ECPR) is a form of intensive life support that has seen increasing use globally to improve outcomes for patients who experience out-of-hospital cardiac arrest (OHCA). Hospitals with advanced critical care capabilities may be interested in launching an ECPR program to offer this support to the patients they serve; however, to do so, they must first consider the significant investment of resources necessary to start and sustain the program. The existing literature describes many single-center ECPR programs and often focuses on inpatient care and patient outcomes in hospitals with cardiac surgery capabilities. However, building a successful ECPR program and using this technology to support an individual patient experiencing refractory cardiac arrest secondary to a shockable rhythm depends on efficient out-of-hospital and emergency department (ED) management. This article describes the process of implementing 2 intensivist-led ECPR programs with limited cardiac surgery capability. We focus on emergency medical services and ED clinician roles in identifying patients, mobilizing resources, initiation and management of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in the ED, and ongoing efforts to improve ECPR program quality. Each center experienced a significant learning curve to reach goals of arrest-to-flow times of cannulation for ECPR. Building consensus from multidisciplinary stakeholders, including out-of-hospital stakeholders; establishing shared expectations of ECPR outcomes; and ensuring adequate resource support for ECPR activation were all key lessons in improving our ECPR programs.

摘要

体外心肺复苏(ECPR)是一种强化生命支持形式,在全球范围内越来越多地被用于提高院外心脏骤停(OHCA)患者的预后。拥有先进重症监护能力的医院可能有兴趣推出 ECPR 计划,为他们所服务的患者提供这种支持;然而,要做到这一点,他们必须首先考虑启动和维持该计划所需的大量资源投入。现有文献描述了许多单中心 ECPR 计划,并且通常侧重于具有心脏手术能力的医院的住院患者护理和患者预后。然而,建立一个成功的 ECPR 计划并使用这项技术来支持因可电击节律而出现难治性心脏骤停的个体患者,取决于高效的院外和急诊科(ED)管理。本文描述了在心脏手术能力有限的情况下实施 2 个由重症监护医生主导的 ECPR 计划的过程。我们专注于紧急医疗服务和 ED 临床医生在识别患者、调动资源、启动和管理 ED 中的静脉-动脉体外膜肺氧合(VA-ECMO)以及持续努力提高 ECPR 计划质量方面的作用。每个中心都经历了一个显著的学习曲线,以达到 ECPR 插管的到达-血流时间目标。建立多学科利益相关者(包括院外利益相关者)的共识;确立对 ECPR 结果的共同期望;并确保 ECPR 激活的充足资源支持,这些都是改善我们的 ECPR 计划的关键经验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/11803576/c189a81178af/nihms-2050217-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/11803576/c7af15a33384/nihms-2050217-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/11803576/d8c9863b6fa7/nihms-2050217-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/11803576/c189a81178af/nihms-2050217-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/11803576/c7af15a33384/nihms-2050217-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/11803576/d8c9863b6fa7/nihms-2050217-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d58/11803576/c189a81178af/nihms-2050217-f0003.jpg

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本文引用的文献

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Front Med (Lausanne). 2023 Aug 23;10:1239006. doi: 10.3389/fmed.2023.1239006. eCollection 2023.
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Extracorporeal cardiopulmonary resuscitation for refractory OHCA: lessons from three randomized controlled trials-the trialists' view.体外心肺复苏治疗难治性 OHCA:三项随机对照试验的经验教训——试验者的观点。
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Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest.
院外难治性心脏骤停的早期体外心肺复苏
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