Department of Ophthalmology, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.
Int Ophthalmol. 2024 Feb 7;44(1):18. doi: 10.1007/s10792-024-02966-5.
To evaluate the corneal epithelial mapping, ocular surface parameters and their relationship with each other in lower eyelid ectropion patients according to severity.
This retrospective study included 48 lower eyelid ectropion patients and 63 healthy individuals as control group. Ocular surface and tear functions were evaluated with ocular surface staining score, tear film break-up time (BUT), non-invasive tear break-up time (NIBUT) and ocular surface disease index (OSDI). Meibography scores and corneal epithelial thickness (CET) mapping were evaluated. The lower eyelid ectropion was classified and divided into subgroups as follows: mild, moderate and severe.
There was no significant differences between the groups for age and gender. Compared to controls, CET was significantly thinner at inferior (p = 0.047) and inferior nasal quadrants (p = 0.023) in the ectropion patients. Lower BUT and NIBUT, higher OSDI scores and higher ocular surface staining were observed in the ectropion patients. In the subgroups determined according to the severity of ectropion, ocular surface damage was found to be significantly higher as the severity of ectropion increased (p < 0.05).
Patients with lower eyelid ectropion had worse ocular surface findings and more ocular complaints. Furthermore, the inferior and inferior nasal CETs were thinner in patients with lower ectropion.
根据严重程度评估下眼睑外翻患者的角膜上皮绘图、眼表参数及其相互关系。
本回顾性研究纳入了 48 名下眼睑外翻患者和 63 名健康个体作为对照组。通过眼表面染色评分、泪膜破裂时间（BUT）、非侵入性泪膜破裂时间（NIBUT）和眼表面疾病指数（OSDI）评估眼表和泪液功能。评估了睑板腺照相评分和角膜上皮厚度（CET）绘图。将下眼睑外翻分为轻度、中度和重度，并进一步分为亚组。
组间年龄和性别无显著差异。与对照组相比，外翻患者的下眼睑和下鼻象限的 CET 明显变薄（p = 0.047 和 p = 0.023）。外翻患者的 BUT 和 NIBUT 较低、OSDI 评分较高、眼表面染色较重。根据外翻严重程度确定的亚组中，随着外翻程度的加重，眼表面损伤明显增加（p < 0.05）。
下眼睑外翻患者的眼表状况较差，眼主诉更多。此外，下眼睑轻度外翻患者的下眼睑和下鼻侧 CET 较薄。
