Department of Ophthalmology, Ankara Ulucanlar Eye Training and Research Hospital, Altındag, Ankara, Turkey.
Department of Ophthalmology, Faculty of Medicine, Ankara University, Ankara, Turkey.
Int Ophthalmol. 2024 Feb 7;44(1):23. doi: 10.1007/s10792-024-02928-x.
To evaluate and compare the findings of MP and OCT in patients with inactive Behçet's uveitis (BU).
Sixty-five eyes of 38 patients were included in this retrospective study. Ophthalmologic examination findings and OCT and MP results were recorded. The relationship between best corrected visual acuity (BCVA), duration of uveitis, central macular thickness (CMT), presence of photoreceptor zone (PZ), and/or retinal pigment epithelium (RPE) damage, macular integrity index, mean threshold and fixation stability was analyzed.
There was a positive correlation between BCVA and CMT (p < 0.001). The eyes with PZ and/or RPE damage had significantly lower visual acuity (p < 0.001). There was a negative correlation between BCVA and macular integrity index (p = 0.005). BCVA showed positive correlations with mean threshold and fixation stability [(BCVA vs. mean threshold, p < 0.001), (BCVA vs. P1, p < 0.001), and (BCVA vs. P2, p < 0.001)]. While there was no significant correlation between CMT and macular integrity index (p = 0.08), both mean threshold and fixation stability were significantly positively correlated with CMT [(CMT vs. mean threshold, p = 0.01), (CMT vs. P1, p = 0.008), and (CMT vs. P2, p = 0.005)]. Mean threshold and fixation stability (P1 and P2) were significantly lower in the eyes with PZ and/or RPE damage (p = 0.008, p = 0.02, and p = 0.01, respectively).
MP showed results consistent with visual acuity and morphological findings by OCT in patients with inactive BU. Although MP is promising for patient follow-up, controlled prospective studies are needed.
评估和比较静止期 Behcet 葡萄膜炎(BU)患者的多焦视网膜电图(MP)和光相干断层扫描(OCT)的结果。
本回顾性研究纳入了 38 例患者的 65 只眼。记录了眼科检查结果、OCT 和 MP 结果。分析了最佳矫正视力(BCVA)、葡萄膜炎持续时间、中心黄斑厚度(CMT)、光感受器带(PZ)和/或视网膜色素上皮(RPE)损伤、黄斑完整性指数、平均阈值和固视稳定性与 BCVA 的关系。
BCVA 与 CMT 呈正相关(p<0.001)。有 PZ 和/或 RPE 损伤的眼视力明显较低(p<0.001)。BCVA 与黄斑完整性指数呈负相关(p=0.005)。BCVA 与平均阈值和固视稳定性呈正相关[(BCVA 与平均阈值,p<0.001),(BCVA 与 P1,p<0.001),和(BCVA 与 P2,p<0.001)]。虽然 CMT 与黄斑完整性指数无显著相关性(p=0.08),但平均阈值和固视稳定性均与 CMT 呈显著正相关[(CMT 与平均阈值,p=0.01),(CMT 与 P1,p=0.008),和(CMT 与 P2,p=0.005)]。有 PZ 和/或 RPE 损伤的眼的平均阈值和固视稳定性(P1 和 P2)明显较低(p=0.008、p=0.02 和 p=0.01)。
MP 在静止期 BU 患者中的结果与 OCT 检测的视力和形态学结果一致。尽管 MP 对患者随访有一定的前景,但仍需要进行对照前瞻性研究。