Department of Ophthalmology, Faculty of Medicine, Ankara University, Ankara, Turkey.
Department of Opthalmology, Kırşehir Ahi Evran Training and Research Hospital, Kırşehir, Turkey.
Int Ophthalmol. 2021 May;41(5):1753-1761. doi: 10.1007/s10792-021-01734-z. Epub 2021 Feb 9.
To evaluate spectral domain optical coherence tomography (SD-OCT) findings of 42 eyes with pars planitis and to identify risk factors affecting visual acuity.
Medical records and SD-OCT findings were retrospectively reviewed.
Mean best-corrected visual acuity (BCVA) was 0.248 ± 0.3 on the logMAR scale at baseline. SD-OCT findings included epiretinal membrane (ERM) in 16 (38.1%) eyes, loss of normal foveal contour appearance in 8 (19.0%), ellipsoid zone (EZ) damage in 5 (11.9%), external limiting membrane (ELM) damage in 3 (7.1%), disruption of retinal pigment epithelium (RPE) in 2 (4.8%), and macular atrophy in 1 (2.4%). There was macular edema in 10 (23.8%) eyes [cystoid macular edema (CME) in 8 (19.0%), diffuse macular edema (DME) in 6 (14.3%), and serous retinal detachment in 2 (4.8%)]. The mean central macular thickness (CMT) was 272.1 ± 319.5 μm. Patients were followed up for a mean of 50.6 ± 36.7 months. Mean BCVA was 0.210 ± 0.3 at the final evaluation. SD-OCT findings included ERM in 28 (66.7%) eyes, EZ damage in 6 (14.3%), ELM damage in 3 (7.1%), disruption of RPE in 4 (9.5%), loss of normal foveal contour appearance in 12 (28.6%), and macular atrophy in 2 (4.8%). There was CME and/or DME in 6 (14.3%) eyes. The mean CMT was 238 ± 220.9 μm and was significantly lower than the baseline (p < 0.001). According to multivariate linear regression analysis, the presence of DME, and loss of normal foveal contour appearance at baseline were the independent factors associated with BCVA at the final examination (B = 0.726, p < 0.001; B = 0.766, p < 0.001, respectively).
DME and loss of normal foveal contour appearance were more likely to have adverse effects on visual acuity.
评估 42 例中间葡萄膜炎的光相干断层扫描（SD-OCT）表现，并确定影响视力的相关危险因素。
回顾性分析患者的病历资料和 SD-OCT 检查结果。
患者平均最佳矫正视力（BCVA）在基线时为 logMAR 视力 0.248 ± 0.3。SD-OCT 检查结果包括 16 只眼（38.1%）出现视网膜内表面膜（ERM），8 只眼（19.0%）出现正常黄斑区形态丧失，5 只眼（11.9%）出现椭圆体带（EZ）损害，3 只眼（7.1%）出现外界膜（ELM）损害，2 只眼（4.8%）出现视网膜色素上皮层（RPE）破坏，1 只眼（2.4%）出现黄斑萎缩。10 只眼（23.8%）出现黄斑水肿[8 只眼（19.0%）为囊样黄斑水肿（CME），6 只眼（14.3%）为弥漫性黄斑水肿（DME），2 只眼（4.8%）为浆液性视网膜脱离]。黄斑中心厚度（CMT）的平均为 272.1 ± 319.5μm。患者平均随访时间为 50.6 ± 36.7 个月。末次随访时平均 BCVA 为 0.210 ± 0.3。SD-OCT 检查结果包括 28 只眼（66.7%）出现 ERM，6 只眼（14.3%）出现 EZ 损害，3 只眼（7.1%）出现 ELM 损害，4 只眼（9.5%）出现 RPE 破坏，12 只眼（28.6%）出现正常黄斑区形态丧失，2 只眼（4.8%）出现黄斑萎缩。6 只眼（14.3%）存在 CME 和/或 DME。CMT 的平均为 238 ± 220.9μm，明显低于基线水平（p < 0.001）。多变量线性回归分析显示，基线时存在 DME 和正常黄斑区形态丧失是与最终检查时 BCVA 相关的独立因素（B = 0.726，p < 0.001；B = 0.766，p < 0.001）。
DME 和正常黄斑区形态丧失更可能对视力产生不良影响。
