Department of Pediatric Gastroenterology, Hepatology and Nutrition, Dr Rela Institute & Medical Centre, Bharath Institute of Higher Education and Research, Chennai, India.
Indian J Pediatr. 2024 Apr;91(4):366-373. doi: 10.1007/s12098-024-05036-x. Epub 2024 Feb 7.
In liver disease, there is derangement of appetite, digestion, absorption, assimilation, storage and metabolism of both macro and micronutrients. These derangements have an impact on mortality and morbidity associated with liver diseases. In infants, breast feeds should not be stopped unless there are compelling reasons such as underlying metabolic problem. Parenteral nutrition should be considered only if, oral or nasogastric feeding is not possible. The effect of malnutrition on liver disease and impact of liver failure on nutrition is vicious and nutritional intervention has to be done at the earliest to break that vicious cycle. This chapter gives an overview of nutritional management in acute and chronic liver diseases in children and also its impact on specific clinical scenarios including liver transplantation.
在肝脏疾病中，存在对宏量和微量营养素的食欲、消化、吸收、同化、储存和代谢的紊乱。这些紊乱对与肝脏疾病相关的死亡率和发病率有影响。在婴儿中，除非有基础代谢问题等强制性原因，否则不应停止母乳喂养。只有在无法进行口服或鼻胃喂养的情况下，才应考虑肠外营养。营养不良对肝脏疾病的影响以及肝功能衰竭对营养的影响是恶性循环的，必须尽早进行营养干预以打破这种恶性循环。本章概述了儿童急性和慢性肝脏疾病的营养管理，以及其对包括肝移植在内的特定临床情况的影响。
