IVI Alicante, Centro de Excelencia en Rejuvenecimiento Ovárico, Avenida de Denia, Alicante, Spain.
Curr Opin Obstet Gynecol. 2024 Jun 1;36(3):118-123. doi: 10.1097/GCO.0000000000000944. Epub 2024 Feb 5.
This review aims to elucidate potential variations in clinical outcomes resulting from the use of different types of platelet-rich plasma (PRPs) in reproductive medicine. It seeks to explore the reasons behind the diverse results reported in various studies and assess the general features distinguishing different PRP formulations.
PRPs have found applications across diverse medical fields, generating controversy due to the variability in outcomes. The field of reproductive medicine, despite its limited published studies, is encountering a similar challenge as it integrates these treatments.
The multitude of PRP product brands in the market, coupled with 'home-made' PRPs, poses a significant barrier to establishing a common protocol for the preparation of standardized PRP products. This impediment hinders widespread adoption by clinicians, particularly in endometrial or ovarian treatments. Drawing from evidence in other medical disciplines, this review endeavors to compile essential characteristics that PRPs must possess, aiming to mitigate the impact of variables affecting results in forthcoming studies.
本综述旨在阐明生殖医学中使用不同类型富血小板血浆（PRP）导致临床结果潜在差异的原因。本文探讨了造成不同研究报告结果多样性的原因，并评估了区分不同 PRP 配方的一般特征。
PRP 在多个医学领域得到了应用，但由于结果的可变性，引起了争议。生殖医学领域，尽管发表的研究有限，但在整合这些治疗方法时也面临着类似的挑战。
市场上PRP 产品品牌众多，再加上“自制”PRP，这给制备标准化 PRP 产品的通用方案带来了重大障碍。这一障碍阻碍了临床医生的广泛采用，特别是在子宫内膜或卵巢治疗方面。本综述借鉴了其他医学学科的证据，努力总结 PRP 必须具备的基本特征，旨在减轻影响未来研究结果的变量的影响。
