5-Fluorouracil concentrations in human plasma following R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur) administration. - Suppr | 超能文献

5-Fluorouracil concentrations in human plasma following R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur) administration.

作者信息

Au J L, Sadée W

出版信息

Cancer Res. 1979 Oct;39(10):4289-90.

Abstract

摘要

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5-Fluorouracil concentrations in human plasma following R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur) administration.

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Fluorescence determination of 5-fluorouracil and 1-(tetrahydro-2-furanyl)-5-fluorouracil in blood serum by high-performance liquid chromatography.

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[Sequential changes in blood concentrations of tegafur and 5-FU during oral administration of fine granules of tegafur in patients with primary liver cancer].[原发性肝癌患者口服替加氟细粒剂期间替加氟和5-氟尿嘧啶血药浓度的序贯变化]

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Human urinary metabolites of 1-(tetrahydro-2-furanyl)-5-fluorouracil (ftoraful).

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Metabolic activation of R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur) to 5-fluorouracil by soluble enzymes.R,S-1-(四氢-2-呋喃基)-5-氟尿嘧啶（替加氟）通过可溶性酶代谢活化为5-氟尿嘧啶。

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High-pressure liquid chromatographic determination of ftorafur [1-(tetrahydro-2-furanyl)-5-fluorouracil] and GLC-mass spectrometric determination of 5-fluorouracil and uracil in biological materials after oral administration of uracil plus ftorafur.

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The pharmacology of ftorafur (R, S-1-(tetrahydro-2-furanyl)-5-fluorouracil.呋氟尿嘧啶（R，S-1-（四氢-2-呋喃基）-5-氟尿嘧啶）的药理学

Recent Results Cancer Res. 1981;76:100-14. doi: 10.1007/978-3-642-81565-2_9.

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Improved liquid chromatographic assay for serum fluorouracil concentrations in the presence of ftorafur.在存在呋喃氟尿嘧啶的情况下用于测定血清氟尿嘧啶浓度的改进型液相色谱分析法。

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Effects of 5-Fluorouracil prodrugs on the central nervous system in mice and rats.5-氟尿嘧啶前药对小鼠和大鼠中枢神经系统的影响。

Pharm Res. 1985 Mar;2(2):83-6. doi: 10.1023/A:1016394829072.

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Changes in toxic and antitumor properties of ftorafur by induction or inhibition of the microsomal enzymes activity.

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Hepatic conversion of 1-(tetrahydro-2-furanyl)-5-fluorouracil into 5-fluorouracil in patients with hepatocellular carcinoma.

Gastroenterol Jpn. 1987 Feb;22(1):55-62. doi: 10.1007/BF02806335.

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Oral tegafur in the treatment of gastrointestinal tract cancers: a phase II study.口服替加氟治疗胃肠道癌症：一项II期研究。

Br J Cancer. 1990 Mar;61(3):475-8. doi: 10.1038/bjc.1990.105.