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估算肯尼亚青少年艾滋病毒护理就诊和促进向成人护理过渡的干预措施的成本。

Estimating the costs of adolescent HIV care visits and an intervention to facilitate transition to adult care in Kenya.

机构信息

The Comparative Health Outcomes, Policy, and Economics (CHOICE) Institute, University of Washington, Seattle, Washington, United States of America.

Department of Global Health, School of Public Health, University of Washington, Seattle, Washington, United States of America.

出版信息

PLoS One. 2024 Feb 8;19(2):e0296734. doi: 10.1371/journal.pone.0296734. eCollection 2024.

DOI:10.1371/journal.pone.0296734
PMID:38330069
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10852328/
Abstract

INTRODUCTION

Adolescents with HIV in sub-Saharan Africa face challenges transitioning to adult HIV care, which can affect long-term HIV care adherence and retention. An adolescent transition package (ATP) focused on transition tools can improve post-transition clinical outcomes, but its implementation costs are unknown.

METHODS

We estimated the average cost per patient of an HIV care visit and ATP provision to adolescents. Data was collected from 13 HIV clinics involved in a randomized clinical trial evaluating ATP in western Kenya. We conducted a micro-costing and activity-driven time estimation to assess costs from the provider perspective. We developed a flow-map, conducted staff interviews, and completed time and motion observation. ATP costs were estimated as the difference in average cost for an HIV care transition visit in the intervention compared to control facilities. We assessed uncertainty in costing estimates via Monte Carlo simulations.

RESULTS

The average cost of an adolescent HIV care visit was 29.8USD (95%CI 27.5, 33.4) in the standard of care arm and 32.9USD (95%CI 30.5, 36.8) in the ATP intervention arm, yielding an incremental cost of 3.1USD (95%CI 3.0, 3.4) for the ATP intervention. The majority of the intervention cost (2.8USD) was due ATP booklet discussion with the adolescent.

CONCLUSION

The ATP can be feasibly implemented in HIV care clinics at a modest increase in overall clinic visit cost. Our cost estimates can be used to inform economic evaluations or budgetary planning of adolescent HIV care interventions in Kenya.

摘要

简介

撒哈拉以南非洲的青少年艾滋病毒感染者在过渡到成人艾滋病毒护理方面面临挑战,这会影响长期的艾滋病毒护理依从性和保留率。以过渡工具为重点的青少年过渡方案 (ATP) 可以改善过渡后的临床结局,但实施成本尚不清楚。

方法

我们估计了每位患者接受艾滋病毒护理就诊和提供 ATP 给青少年的平均成本。数据来自参与在肯尼亚西部评估 ATP 的随机临床试验的 13 个艾滋病毒诊所。我们进行了微观成本核算和活动驱动的时间估计,以从提供者的角度评估成本。我们制定了流程图,进行了员工访谈,并完成了时间和动作观察。ATP 成本被估计为干预组与对照组的艾滋病毒护理过渡就诊的平均成本差异。我们通过蒙特卡罗模拟评估成本估算的不确定性。

结果

在标准护理组,青少年艾滋病毒护理就诊的平均费用为 29.8 美元(95%CI 27.5,33.4),在 ATP 干预组为 32.9 美元(95%CI 30.5,36.8),ATP 干预的增量成本为 3.1 美元(95%CI 3.0,3.4)。干预的大部分成本(2.8 美元)是由于与青少年讨论 ATP 手册。

结论

ATP 可以在艾滋病毒护理诊所中切实实施,总就诊费用略有增加。我们的成本估算可用于为肯尼亚的青少年艾滋病毒护理干预措施进行经济评估或预算规划提供信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c5c/10852328/24572aead30a/pone.0296734.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c5c/10852328/22c13f9b610d/pone.0296734.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c5c/10852328/c0c6bece5781/pone.0296734.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c5c/10852328/4b90b6e378e7/pone.0296734.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c5c/10852328/6a4553febb4b/pone.0296734.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c5c/10852328/24572aead30a/pone.0296734.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c5c/10852328/22c13f9b610d/pone.0296734.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c5c/10852328/c0c6bece5781/pone.0296734.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c5c/10852328/4b90b6e378e7/pone.0296734.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c5c/10852328/6a4553febb4b/pone.0296734.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c5c/10852328/24572aead30a/pone.0296734.g005.jpg

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Adolescent transition to adult care for HIV-infected adolescents in Kenya (ATTACH): study protocol for a hybrid effectiveness-implementation cluster randomised trial.
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