Hagberg B, Gustafson L
Arch Gerontol Geriatr. 1985 Dec;4(4):321-32. doi: 10.1016/0167-4943(85)90039-1.
Patients with early as well as manifest dementia were studied in a longitudinal way with psychometric and psychiatric methods. Tests such as vocabulary, attention test, block design test, verbal and spatial memory tests, reaction time test and examination for aphasia were used as well as a qualitative analysis of behaviour and personality. The differential diagnosis of Alzheimer's disease, Pick's disease and other dementias with fronto-temporal degeneration and multi-infarct dementia was based on diagnostic rating scales. Differences in cognitive profiles, qualities of behaviour and scores on combinations of psychiatric rating scales were identified for pathoanatomically verified cases with Alzheimer's disease, fronto-temporal degeneration and multi-infarct dementia.
采用心理测量和精神病学方法,对早期和明显痴呆患者进行了纵向研究。使用了诸如词汇测试、注意力测试、积木设计测试、言语和空间记忆测试、反应时间测试以及失语症检查等测试,同时对行为和人格进行了定性分析。阿尔茨海默病、皮克病以及其他伴有额颞叶变性的痴呆症和多发梗死性痴呆的鉴别诊断基于诊断评定量表。针对经病理解剖证实的阿尔茨海默病、额颞叶变性和多发梗死性痴呆病例,确定了认知特征、行为特质以及精神病评定量表组合得分方面的差异。