Department of Pharmacy, Bahir Dar University College of Medical and Health Sciences, Bahir Dar, Amhara, Ethiopia.
Department of Pharmacy, Wollo University, Dessie, Ethiopia.
BMJ Open. 2024 Feb 8;14(2):e081744. doi: 10.1136/bmjopen-2023-081744.
The aim of this study was to assess the adequacy of cancer-related pain (CRP) management and associated factors among patients with cancer in the Northwest oncology centres of Ethiopia.
An institutional-based multicentre cross-sectional study was conducted among patients with cancer in the Northwest oncology centres of Ethiopia from May to July 2022.
All oncology patients at selected hospitals who fulfilled the inclusion criteria during the data collection period were the study population.
The main outcome of this study was the adequacy of CRP management, which was measured by the Pain Management Index (PMI). A systematic random sampling technique was used to select representatives from each study area. Data entry and analysis were done using EpiData V.4.6.1 and SPSS V.26, respectively. Binary logistic regression was conducted to determine independent predictors of the adequacy of CRP management. A p value of <0.05 was considered statistically significant.
From a total of 422 included respondents, about 67.5% of the participants had adequate CRP management (95% CI 62.8 to 72). Good performance status (adjusted OR (AOR)=0.44; 95% CI 0.24 to 0.80), presence of comorbidity (AOR=3.28; 95% CI 1.68 to 6.38) and pain history (AOR=0.33; 95% CI 0.01 to 0.11) were significantly associated with the adequacy of cancer pain management.
Using PMI status in the Northwest oncology centre of Ethiopia, more than two-thirds of patients with CRP obtained adequate pain management. The adequacy of CRP management was found to be influenced by factors like comorbidity, past pain history and Eastern cooperative oncology group performance status.
本研究旨在评估埃塞俄比亚西北部肿瘤中心癌症相关疼痛(CRP)管理的充分性及其相关因素。
这是一项在 2022 年 5 月至 7 月期间在埃塞俄比亚西北部肿瘤中心进行的基于机构的多中心横断面研究。
在数据收集期间符合纳入标准的所有选定医院的癌症患者均为研究人群。
本研究的主要结果是 CRP 管理的充分性,通过疼痛管理指数(PMI)来衡量。采用系统随机抽样技术从每个研究区域选择代表。使用 EpiData V.4.6.1 和 SPSS V.26 分别进行数据录入和分析。采用二元逻辑回归分析确定 CRP 管理充分性的独立预测因素。p 值 <0.05 被认为具有统计学意义。
在总共纳入的 422 名受访者中,约 67.5%的参与者 CRP 管理充分(95%CI 62.8 至 72)。良好的身体状况(调整后的比值比(AOR)=0.44;95%CI 0.24 至 0.80)、合并症(AOR=3.28;95%CI 1.68 至 6.38)和疼痛史(AOR=0.33;95%CI 0.01 至 0.11)与癌症疼痛管理的充分性显著相关。
在埃塞俄比亚西北部肿瘤中心,使用 PMI 状态,超过三分之二的 CRP 患者获得了充分的疼痛管理。CRP 管理的充分性受到合并症、既往疼痛史和东部合作肿瘤组表现状态等因素的影响。