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巴基斯坦晚期癌症患者疼痛控制的充分性

Adequacy of Pain Control in Patients With Advanced Cancer in Pakistan.

作者信息

Majeed Muhammad Hassan, Nadeem Ramsha, Khokhar Muhammad Abbas, Qaisar Muhammad Nawaz

机构信息

1 Natchaug Hospital, Mansfield Center, CT, USA.

2 Mayo Hospital, Lahore, Pakistan.

出版信息

J Palliat Care. 2019 Apr;34(2):126-131. doi: 10.1177/0825859718800490. Epub 2018 Sep 13.

Abstract

PURPOSE

: Pain is highly prevalent in advanced cancer and requires aggressive management. However, pain management in cancer is minimally investigated in Pakistan. This cross-sectional study explores the adequacy of pain management in patients with advanced stage cancer in Pakistan.

METHOD

: From January 2017 to May 2017, a cross-sectional study was conducted at Mayo Hospital, Lahore, Pakistan. A total of 218 patients with cancers were interviewed, and 136 patients with pain ≥5 on a Numerical Rating Scale for pain were included in the study. Demographic of patients and clinical characteristics of tumors were also evaluated.

RESULTS

: Only about one-third of the patients with advanced cancer reported adequate pain management. Chi-square test, χ (1, n = 136) = 33.038, P < .05, indicated that pain scores were inversely associated with pain control; inadequate pain control was observed in patients with higher pain score and vice versa. Of the 55.88% of patients who were prescribed morphine, only 6 patients were compliant with treatment recommendations. Most patients were prescribed nonopioid medications and tramadol and codeine, which are weak opioid medications.

CONCLUSION

: The rate of undertreatment of cancer pain in Pakistan is alarming. Inadequate clinicians' training, patients' and caregivers' beliefs, lack of availability of opioid medications, and socioeconomic factors are some of the barriers to effective pain control. A multidisciplinary team approach is necessary to follow the World Health Organization pain ladder guidelines for the treatment of cancer pain.

摘要

目的

疼痛在晚期癌症中极为普遍,需要积极治疗。然而,巴基斯坦对癌症疼痛管理的研究极少。这项横断面研究探讨了巴基斯坦晚期癌症患者疼痛管理的充分性。

方法

2017年1月至2017年5月,在巴基斯坦拉合尔的梅奥医院进行了一项横断面研究。共采访了218例癌症患者,其中136例疼痛数字评分量表(Numerical Rating Scale for pain)评分≥5的患者纳入研究。还评估了患者的人口统计学特征和肿瘤的临床特征。

结果

只有约三分之一的晚期癌症患者报告疼痛得到了充分管理。卡方检验,χ(1,n = 136)= 33.038,P <.05,表明疼痛评分与疼痛控制呈负相关;疼痛评分较高的患者疼痛控制不足,反之亦然。在开具吗啡处方的55.88%的患者中,只有6例患者遵循了治疗建议。大多数患者开具的是非阿片类药物以及曲马多和可待因,后者是弱阿片类药物。

结论

巴基斯坦癌症疼痛治疗不足的比例令人担忧。临床医生培训不足、患者及护理人员的观念、阿片类药物供应不足以及社会经济因素是有效控制疼痛的一些障碍。遵循世界卫生组织癌症疼痛治疗阶梯指南需要采用多学科团队方法。

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