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肝脏形态异常及其临床意义的综述

A general review of anomalies of hepatic morphology and their clinical implications.

作者信息

Champetier J, Yver R, Létoublon C, Vigneau B

出版信息

Anat Clin. 1985;7(4):285-99. doi: 10.1007/BF01784645.

Abstract

Anomalies of hepatic morphology, as opposed to anatomical variations, are rare. Nevertheless, knowledge of such anomalies is important since they do not always remain clinically latent. Four case studies of different types of anomalies encountered in surgical practice in the adult are reported herein. A general review of hepatic anomalies can be divided into two categories, i.e. anomalies due to defective development and anomalies due to excessive development of the liver. Such disturbances are sometimes associated with malformations of other structures, especially the diaphragm and suspensory apparatus of the liver. Defective development of the left lobe of the liver can lead to gastric volvulus. Conservely, defective development of the right lobe either remains clinically latent or leads to portal hypertension. Anomalies related to excessive development of the liver lead to formation of accessory lobes annexed to the liver. Despite their diversity of shape, size and location, such accessory lobes have common features allowing them to be considered as an entity. In most cases the accessory lobe is found in the infra-hepatic position. Riedel's lobe is the best known example of a sessile accessory lobe. Accessory lobes may also stimulate tumor. In cases where the accessory lobe has a pedicle, torsion is a common event leading to discovery of the abnormal mass. The origin of the anomalies of hepatic morphology occurring in the course of organogenesis remains to be elucidated. The use of ultrasonography should now allow identification of such anomalies prior to the occurrence of an acute complication and in the future to possibly detect them in the fetus.

摘要

与肝脏解剖变异不同,肝脏形态异常较为罕见。然而,了解此类异常很重要,因为它们并非总是在临床上保持隐匿状态。本文报告了在成人外科实践中遇到的四种不同类型异常的病例研究。肝脏异常的总体回顾可分为两类,即发育缺陷导致的异常和肝脏过度发育导致的异常。此类紊乱有时与其他结构的畸形有关,尤其是膈肌和肝脏的悬韧带。肝左叶发育缺陷可导致胃扭转。相反,肝右叶发育缺陷要么在临床上保持隐匿状态,要么导致门静脉高压。与肝脏过度发育相关的异常会导致肝脏附属叶的形成。尽管这些附属叶在形状、大小和位置上各不相同,但它们具有共同特征,可被视为一个实体。在大多数情况下,附属叶位于肝下位置。里德尔叶是最著名的无蒂附属叶的例子。附属叶也可能刺激肿瘤形成。在附属叶有蒂的情况下,扭转是导致发现异常肿块的常见情况。器官发生过程中出现的肝脏形态异常的起源仍有待阐明。现在,超声检查的应用应能在急性并发症发生之前识别此类异常,并在未来可能在胎儿中检测到它们。

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