Ahmad Ibtihal, Alkomi Saja, Sharaha Rula, Manasrah Shaheera, Dukmak Osama N
Nephrology, Internal Medicine, School of Medicine, Palestine Polytechnic University, Hebron, PSE.
Nephrology, Internal Medicine, School of Medicine, Al-Quds University, Jerusalem, PSE.
Cureus. 2024 Jan 9;16(1):e51956. doi: 10.7759/cureus.51956. eCollection 2024 Jan.
Sagliker syndrome (SS) is a rare complication in patients with chronic kidney disease (CKD) on prolonged dialysis due to uncontrolled secondary hyperparathyroidism (SHPT). SS manifests with a constellation of clinical manifestations, including short stature, craniomaxillofacial abnormalities, hearing loss, and neuropsychiatric disorders. This article reports a 33-year-old male patient with CKD who complained of progressive disfiguring facial changes, multiple recurrent fractures, and shortened height. The condition affects his quality of life. On workup, his lab results showed highly elevated serum levels of parathyroid hormone, alkaline phosphatase (ALP), calcium, and phosphate. His comorbidities and poor health status limit his ability to do parathyroidectomy (Ptx). A reliable diagnostic approach must be considered, enabling physicians to make earlier interventions and get better outcomes.
萨利克综合征（SS）是慢性肾脏病（CKD）患者长期透析后因继发性甲状旁腺功能亢进（SHPT）控制不佳而出现的一种罕见并发症。SS表现为一系列临床表现，包括身材矮小、颅颌面异常、听力丧失和神经精神障碍。本文报告了一名33岁的CKD男性患者，他主诉面部逐渐变形、多次反复骨折和身高缩短。这种情况影响了他的生活质量。检查时，他的实验室检查结果显示血清甲状旁腺激素、碱性磷酸酶（ALP）、钙和磷水平高度升高。他的合并症和健康状况不佳限制了他进行甲状旁腺切除术（Ptx）的能力。必须考虑一种可靠的诊断方法，使医生能够更早地进行干预并取得更好的治疗效果。
