Wu Wei, Qian Liyuan, Chen Xuedong, Ding Boni
Department of Breast and THyroid Surgery, Third Xiangya Hospital, Central South University, Changsha 410013, China
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2014 Oct;39(10):1100-4. doi: 10.11817/j.issn.1672-7347.2014.10.020.
We analyzed the characters of Sagliker syndrome by reporting a case of Sagliker syndrome and reviewed literature. We found that Sagliker syndrome had low incidence rate, young onset age, and was more common in women. There were high levels of alkaline phosphatase and parathyroid hormone in the blood of the patients. Patients with Sagliker syndrome with primary onset of non-diabetic nephropathy usually had chronic glomerulonephritis. We thought that secondary hyperparathyroidism in patients with Sagliker syndrome was induced by parathyroid hyperplasia, but high levels of alkaline phosphatase and parathyroid hormone in the blood of the patients with the secondary hyperparathyroidism were the main cause of Sagliker syndrome. Parathyroidectomy could stop the progress of Sagliker syndrome, but it could not reverse the occurrence of skeletal malformation.
