Key Laboratory of Integrated Regulation and Resource Development on Shallow Lake of Ministry of Education, College of Environment, Hohai University, Nanjing 210098, P. R. China.
Yangtze Institute for Conservation and Development, Hohai University, Nanjing 210098, P. R. China.
Anal Chem. 2024 Feb 27;96(8):3470-3479. doi: 10.1021/acs.analchem.3c05098. Epub 2024 Feb 9.
A self-powered photoelectrochemical (PEC) sensor has attracted widespread attention in the field of analysis, but it is still a challenge to enhance its response signals with rational strategies. In this work, a novel self-powered PEC sensing platform was developed for the quantitative detection of gatifloxacin (GAT) based on a photofuel cell consisting of two types of ZIF-derived ZnO/CoO heterojunctions as photoactive materials. Peroxymonosulfate (PMS) was first used as an electron acceptor coupled with a photofuel cell to develop a synergetic signal amplification strategy. In a dual-photoelectrode system, the PMS activation on the ZnO@CoO photocathode not only accelerated electron transfer from the CoO@ZnO photoanode to achieve strong signal intensity but also improved the sensing sensitivity by the oxidation reaction of generated highly active radicals to GAT. Compared with the absence of electron acceptors, the introduction of PMS produced a 2-fold enhancement in the signal output performance and a more than 72-fold improvement in the signal sensitivity. For the construction of the sensing interface, a molecularly imprinted polymer was assembled on the photocathode to specifically recognize GAT. The proposed sensor exhibited a detection range of 10 to 10 pM with a detection limit of 0.065 pM. The proposed sensing method has the advantages of sensitivity, simplicity, reliable stability, and anti-interference ability, which opens the door to the design of high-performance self-powered PEC sensors.
一种自供电光电化学（PEC）传感器在分析领域引起了广泛关注，但仍需要通过合理的策略来增强其响应信号。在这项工作中，基于由两种类型的 ZIF 衍生的 ZnO/CoO 异质结作为光活性材料组成的光燃料电池，开发了一种新型自供电 PEC 传感平台，用于基于光燃料电池的定量检测加替沙星（GAT）。过一硫酸盐（PMS）首先被用作电子受体与光燃料电池结合，以开发协同信号放大策略。在双光电电极系统中，PMS 在 ZnO@CoO 光电阴极上的激活不仅加速了电子从 CoO@ZnO 光阴极的转移，以实现强信号强度，而且通过生成的高活性自由基对 GAT 的氧化反应提高了传感灵敏度。与不存在电子受体相比，引入 PMS 使信号输出性能提高了 2 倍，信号灵敏度提高了 72 倍以上。对于传感界面的构建，将分子印迹聚合物组装在光电阴极上以特异性识别 GAT。所提出的传感器具有 10 到 10 pM 的检测范围和 0.065 pM 的检测限。所提出的传感方法具有灵敏度高、简单、可靠稳定和抗干扰能力强的优点，为高性能自供电 PEC 传感器的设计开辟了道路。
