Lakshmi Hospital, Chittur Road, Palakkad, Kerala, India.
Seth G.S. Medical College & KEM Hospital, Mumbai, Maharashtra, India.
Indian Heart J. 2024 Mar;76 Suppl 1(Suppl 1):S96-S100. doi: 10.1016/j.ihj.2024.01.018. Epub 2024 Feb 8.
Dyslipidemia management in situations like pregnancy, in diseases like rheumatoid arthritis, human immunodeficiency virus (HIV) disease, chronic liver disease, and in the elderly are challenging scenarios. Pregnancy is a contraindication for many drugs. The interaction of various drugs used in HIV infection and rheumatoid arthritis makes it even more difficult to treat with conventional and approved drugs for dyslipidemia. Elderly and chronic renal failure patients often do not tolerate the drugs very well and the data of dyslipidemia management is very different. Lastly, COVID-19 is a unique scenario where clear information is yet to be provided. In this manuscript, the current understanding and available data on the treatment of dyslipidemia in these special situations are discussed.
在某些情况下,如妊娠、类风湿性关节炎、人类免疫缺陷病毒(HIV)疾病、慢性肝病和老年人等,血脂异常的管理是具有挑战性的。许多药物在妊娠期间都禁用。HIV 感染和类风湿性关节炎中使用的各种药物的相互作用使得用常规和批准的药物治疗血脂异常更加困难。老年和慢性肾衰竭患者通常不能很好地耐受这些药物,血脂异常管理的数据也有很大的不同。最后,COVID-19 是一个独特的情况,目前还没有提供明确的信息。本文讨论了在这些特殊情况下血脂异常治疗的现有认识和可用数据。