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竖脊肌平面阻滞在减少结直肠手术后阿片类药物消耗中的效果:一项综合荟萃分析。

Effectiveness of erector spinae plane block in reducing opioid consumption after colorectal surgery: A comprehensive meta-analysis.

机构信息

Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.

Department of Medicine, Karachi Medical and Dental College, Karachi, Pakistan.

出版信息

Am J Surg. 2024 Jun;232:31-44. doi: 10.1016/j.amjsurg.2024.01.032. Epub 2024 Feb 2.

DOI:10.1016/j.amjsurg.2024.01.032
PMID:38336575
Abstract

Despite the life-saving nature of colorectal surgeries, patients often experience intra and post-operative problems, especially pain and discomfort. This meta-analysis aimed to evaluate the effectiveness of erector spinae plane block (ESP block) in postoperative pain management for patients undergoing colorectal surgeries. A comprehensive systematic literature search was conducted in PubMed and Cochrane Library databases from inception until December 2023. Eight studies were deemed appropriate for inclusion. The pooled analysis demonstrated a significant decrease with the ESP block compared to the control group in postoperative opioid consumption [MD ​= ​-15.96 ​mg; 95 ​% CI (-28.74 to -3.18); p ​= ​0.014, I ​= ​87 ​%], intraoperative opioid consumption [MD ​= ​-35.51 ​mg; 95 ​% CI (-62.63 to -8.40); p ​= ​0.010, I ​= ​87 ​%], pain scores [MD ​= ​-0.94; 95 ​% CI (-1.27 to -0.60); p ​< ​0.000001, I ​= ​86 ​%], with a significantly shorter duration of hospital stay [MD ​= ​-1.25 days; 95 ​% CI (-2.02 to -0.48); p ​= ​0.002, I ​= ​23 ​%]. This meta-analysis support the use of erector spinae plane block (ESP) for postoperative pain management in colorectal surgeries. ESP shows significant reductions in opioid consumption, pain scores and hospital stay.

摘要

尽管结直肠手术具有救生性质,但患者经常会经历围手术期问题,尤其是疼痛和不适。本荟萃分析旨在评估竖脊肌平面阻滞(ESP 阻滞)在结直肠手术后患者的术后疼痛管理中的有效性。在 PubMed 和 Cochrane Library 数据库中进行了全面的系统文献检索,检索时间从创建到 2023 年 12 月。有 8 项研究被认为适合纳入。汇总分析表明,与对照组相比,ESP 阻滞组术后阿片类药物消耗[MD=-15.96mg;95%CI(-28.74 至-3.18);p=0.014,I=87%]、术中阿片类药物消耗[MD=-35.51mg;95%CI(-62.63 至-8.40);p=0.010,I=87%]、疼痛评分[MD=-0.94;95%CI(-1.27 至-0.60);p<0.000001,I=86%]均显著降低,住院时间[MD=-1.25 天;95%CI(-2.02 至-0.48);p=0.002,I=23%]显著缩短。这项荟萃分析支持在结直肠手术中使用竖脊肌平面阻滞(ESP)进行术后疼痛管理。ESP 可显著减少阿片类药物消耗、疼痛评分和住院时间。

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