Jara-Cornejo Eduardo, Peña-Bedón Erick, Torres Moya Mahely, Espinoza-Torres Sergio, Sotomayor Maria D P T, Picasso Gino, Tuesta Juan C, López Rosario, Khan Sabir
Technology of Materials for Environmental Remediation (TecMARA) Research Group, Faculty of Sciences, National University of Engineering, Lima 150128, Peru.
Institute of Chemistry, State University of São Paulo (UNESP), Araraquara 14801-970, SP, Brazil.
Polymers (Basel). 2024 Jan 29;16(3):366. doi: 10.3390/polym16030366.
Curcumin is a compound of great importance in the food industry due to its biological and pharmacological properties, which include being an antioxidant, anti-inflammatory, antibacterial, antiviral, and anticarcinogenic. This paper proposes the synthesis of an electrochemical sensor based on molecularly imprinted polymers (MIPs) and MWCNT by drop casting deposited on a glassy carbon electrode (GCE) for the selective quantification of curcumin in food samples. The synthesized compounds are characterized by Fourier transform infrared (IR), Brunauer-Emmett-Teller (BET), and electrochemical techniques such as cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The optimal conditions for further experiments were determined by selecting these parameters. We examined three food products, commercial capsules, turmeric rhizomes, and commercial turmeric powder, employing both electrochemical and HPLC methods for the analysis. The electrochemical method revealed a limit of detection (LOD) value of 0.1365 µmol L, compared with the HPLC analysis, which gave a value of 3.55 µmol L. Furthermore, the MIP material demonstrated superior selectivity for the analyte compared to potential interferents. The recovery percentage, determined using the HPLC method, fell within the range of 87.5% to 102.6.
姜黄素因其生物学和药理学特性在食品工业中是一种非常重要的化合物，这些特性包括抗氧化、抗炎、抗菌、抗病毒和抗癌。本文提出通过滴铸法在玻碳电极（GCE）上沉积基于分子印迹聚合物（MIPs）和多壁碳纳米管（MWCNT）合成一种电化学传感器，用于食品样品中姜黄素的选择性定量分析。合成的化合物通过傅里叶变换红外光谱（IR）、布鲁诺尔-埃米特-泰勒（BET）以及循环伏安法（CV）和差分脉冲伏安法（DPV）等电化学技术进行表征。通过选择这些参数确定了进一步实验的最佳条件。我们使用电化学和高效液相色谱（HPLC）方法对三种食品、商业胶囊、姜黄根茎和商业姜黄粉进行了分析。电化学方法显示检测限（LOD）值为0.1365 μmol/L，相比之下，HPLC分析得出的值为3.55 μmol/L。此外，与潜在干扰物相比，MIP材料对分析物表现出卓越的选择性。使用HPLC方法测定的回收率在87.5%至102.6%范围内。
