Espinoza-Torres Sergio, López Rosario, Sotomayor Maria D P T, Tuesta Juan C, Picasso Gino, Khan Sabir
Technology of Materials for Environmental Remediation Group (TecMARA), Faculty of Sciences, National University of Engineering, Av. Tupac Amaru 210, Rimac 15333, Peru.
Chemistry Institute, São Paulo State University (UNESP), Araraquara 14801-900, Brazil.
Polymers (Basel). 2023 Aug 8;15(16):3332. doi: 10.3390/polym15163332.
Curcumin is the main colorant of the curcuma longa plant, a food with many benefits for human health. This work aims to synthesize a novel molecularly imprinted polymer (MIP) for the selective detection of curcumin in real samples obtained from the local market of Peru. MIPs were synthesized via bulk polymerization using curcumin, acrylamide, ethylene glycol dimethacrylate, ABCV, and acetonitrile. FTIR spectra showed equal spectra for MIP and NIP. N physisorption analysis presented a higher value BET surface for the MIP (28.5 m g) compared to the NIP (18.5 m g). The adsorption capacity of the MIP was evaluated using UV-vis spectrophotometry in the band around 430 nm. The adsorption kinetics found were of pseudo-second-order and a Q value of 16.2 mg g. Furthermore, the adsorption process resembles the Freundlich adsorption model with a heterogeneity factor of less than 1 (0.61) and Kf greater for MIP (1.97). The selectivity test indicated that MIP is more selective for curcumin (Q = 13.20 mg g) than against interferents (Q = 2.19 mg g). The specific selectivity factor (S) obtained for the interferents was greater than 1 which indicates a good selectivity. Finally, the application of MIP in real samples using UV-vis spectrophotometry yielded a recovery value greater than 70%.
姜黄素是姜黄植物的主要色素，姜黄作为一种食物，对人体健康有诸多益处。本研究旨在合成一种新型分子印迹聚合物（MIP），用于选择性检测从秘鲁当地市场获取的实际样品中的姜黄素。通过本体聚合法，以姜黄素、丙烯酰胺、乙二醇二甲基丙烯酸酯、ABCV和乙腈为原料合成了MIP。傅里叶变换红外光谱（FTIR）显示MIP和非印迹聚合物（NIP）的光谱相同。N2物理吸附分析表明，MIP的BET比表面积（28.5 m²/g）高于NIP（18.5 m²/g）。采用紫外可见分光光度法在430 nm左右的波段评估了MIP的吸附容量。发现吸附动力学符合伪二级动力学，Q值为16.2 mg/g。此外，吸附过程符合Freundlich吸附模型，非均质性因子小于1（0.61），MIP的Kf值更大（1.97）。选择性测试表明，MIP对姜黄素的选择性（Q = 13.20 mg/g）高于对干扰物的选择性（Q = 2.19 mg/g）。干扰物的特异性选择性因子（S）大于1，表明具有良好的选择性。最后，使用紫外可见分光光度法将MIP应用于实际样品，回收率大于70%。
