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13年有影响力的微创冠状动脉手术:单支血管和多支血管疾病的短期和长期结果

Thirteen Years of Impactful, Minimally Invasive Coronary Surgery: Short- and Long-Term Results for Single and Multi-Vessel Disease.

作者信息

Ilcheva Lilly, Häussler Achim, Cholubek Magdalena, Ntinopoulos Vasileios, Odavic Dragan, Dushaj Stak, Rodriguez Cetina Biefer Hector, Dzemali Omer

机构信息

Department of Cardiac Surgery, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.

Department of Cardiac Surgery, Zurich City Hospital-Triemli, Birmensdorferstrasse 497, 8055 Zurich, Switzerland.

出版信息

J Clin Med. 2024 Jan 28;13(3):761. doi: 10.3390/jcm13030761.

Abstract

OBJECTIVES

Minimally invasive coronary surgery (MICS) via lateral thoracotomy is a less invasive alternative to the traditional median full sternotomy approach for coronary surgery. This study investigates its effectiveness for short- and long-term revascularization in cases of single and multi-vessel diseases.

METHODS

A thorough examination was performed on the databases of two cardiac surgery programs, focusing on patients who underwent minimally invasive coronary bypass grafting procedures between 2010 and 2023. The study involved patients who underwent either minimally invasive direct coronary artery bypass grafting (MIDCAB) for the revascularization of left anterior descending (LAD) artery stenosis or minimally invasive multi-vessel coronary artery bypass grafting (MICSCABG). Our assessment criteria included in-hospital mortality, long-term mortality, and freedom from reoperations due to failed aortocoronary bypass grafts post-surgery. Additionally, we evaluated significant in-hospital complications as secondary endpoints.

RESULTS

A total of 315 consecutive patients were identified between 2010 and 2023 (MIDCAB 271 vs. MICSCABG 44). Conversion to median sternotomy (MS) occurred in eight patients (2.5%). The 30-day all-cause mortality was 1.3% (n = 4). Postoperative AF was the most common complication postoperatively (n = 26, 8.5%). Five patients were reoperated for bleeding (1.6%), and myocardial infarction (MI) happened in four patients (1.3%). The mean follow-up time was six years (±4 years). All-cause mortality was 10.3% (n = 30), with only five (1.7%) patients having a confirmed cardiac cause. The reoperation rate due to graft failure or the progression of aortocoronary disease was 1.4% (n = 4).

CONCLUSIONS

Despite the complexity of the MICS approach, the results of our study support the safety and effectiveness of this procedure with low rates of mortality, morbidity, and conversion for both single and multi-vessel bypass surgeries. These results underscore further the necessity to implement such programs to benefit patients.

摘要

目的

经侧胸壁切口的微创冠状动脉手术(MICS)是冠状动脉手术中一种侵入性较小的替代传统正中全胸骨切开术的方法。本研究调查其在单支和多支血管疾病病例中进行短期和长期血运重建的有效性。

方法

对两个心脏外科项目的数据库进行了全面检查,重点关注2010年至2023年间接受微创冠状动脉搭桥手术的患者。该研究纳入了接受微创直接冠状动脉搭桥术(MIDCAB)以重建左前降支(LAD)动脉狭窄或微创多支血管冠状动脉搭桥术(MICSCABG)的患者。我们的评估标准包括住院死亡率、长期死亡率以及术后因主动脉冠状动脉搭桥失败而再次手术的情况。此外,我们将严重的住院并发症作为次要终点进行评估。

结果

2010年至2023年间共确定了315例连续患者(MIDCAB 271例 vs. MICSCABG 44例)。8例患者(2.5%)转为正中胸骨切开术(MS)。30天全因死亡率为1.3%(n = 4)。术后房颤是术后最常见的并发症(n = 26,8.5%)。5例患者因出血接受再次手术(1.6%),4例患者发生心肌梗死(MI)(1.3%)。平均随访时间为6年(±4年)。全因死亡率为10.3%(n = 30),只有5例(1.7%)患者确定为心脏原因。因移植失败或主动脉冠状动脉疾病进展导致的再次手术率为1.4%(n = 4)。

结论

尽管MICS方法复杂,但我们的研究结果支持该手术的安全性和有效性,单支和多支血管搭桥手术的死亡率、发病率和转换率均较低。这些结果进一步强调了实施此类项目以使患者受益的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d7c/10856352/03646790cdf7/jcm-13-00761-g001.jpg

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