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慢性硬膜下血肿术后复发危险因素的回顾性分析

Retrospective Analysis of Risk Factors for Recurrence of Chronic Subdural Haematoma after Surgery.

作者信息

Zawy Alsofy Samer, Lewitz Marc, Meyer Kyra, Fortmann Thomas, Wilbers Eike, Nakamura Makoto, Ewelt Christian

机构信息

Department of Medicine, Faculty of Health, Witten/Herdecke University, 58448 Witten, Germany.

Department of Neurosurgery, St. Barbara-Hospital, Academic Hospital of Westfaelische Wilhelms-University Muenster, 59073 Hamm, Germany.

出版信息

J Clin Med. 2024 Jan 30;13(3):805. doi: 10.3390/jcm13030805.

Abstract

(1) : In this study, epidemiological, clinical, therapeutical, and haemostaseological variables were investigated regarding their correlation with the recurrence of chronic subdural haematomas to assess the risk of recurrence more reliably in everyday clinical practice. (2) : In our retrospective study, the electronic records of 90 patients who underwent surgery for a chronic subdural haematoma at our institute between 1 January 2017 and 31 May 2021 were analysed regarding previously defined variables. (3) : In the patient collective, 33.33% of the 90 patients experienced a recurrence requiring treatment. The occurrence of a recurrence was not statistically significantly related to age, gender, known alcohol abuse, a specific location, extension over one or both hemispheres, the surgical method, or anticoagulant medication. However, the recurrence was statistically significantly related to haematoma width ( = 0.000007), septation ( = 0.005), and the existence of a coagulation disorder not treated with medication ( = 0.04). (4) : In our study, the width of the haematoma, septation, and coagulation disorders not treated with medication were documented as risk factors for the occurrence of a chronic subdural haematoma. Identifying of these risk factors could help in adapting individual therapeutic concepts for chronic subdural haematomas.

摘要

(1):在本研究中,对流行病学、临床、治疗及止血学变量与慢性硬膜下血肿复发的相关性进行了调查,以在日常临床实践中更可靠地评估复发风险。(2):在我们的回顾性研究中,分析了2017年1月1日至2021年5月31日期间在我院接受慢性硬膜下血肿手术的90例患者的电子记录中的预先定义变量。(3):在这90例患者中,33.33%经历了需要治疗的复发。复发的发生与年龄、性别、已知的酒精滥用、特定位置、累及一个或两个半球、手术方法或抗凝药物使用无统计学显著相关性。然而,复发与血肿宽度(=0.000007)、分隔(=0.005)以及未药物治疗的凝血障碍(=0.04)有统计学显著相关性。(4):在我们的研究中,血肿宽度、分隔以及未药物治疗的凝血障碍被记录为慢性硬膜下血肿发生的风险因素。识别这些风险因素有助于调整慢性硬膜下血肿的个体化治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/402a/10856185/78e659e18cbe/jcm-13-00805-g001.jpg

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