School of Pharmacy, Shandong Second Medical University, Weifang 261053, China.
Weifang City Inspection and Testing Center, Weifang 261100, China.
Molecules. 2024 Feb 4;29(3):718. doi: 10.3390/molecules29030718.
(A. Juss.) Roem., which is widely distributed in China, is a homologous plant resource of medicine and food. The leaves, seeds, barks, buds and pericarps of can be used as medicine with traditional efficacy. Due to its extensive use in traditional medicine in the ancient world, the plant has significant development potential. In this review, 206 compounds, including triterpenoids (-), sesquiterpenoids (-), diterpenoids (-), sterols (-), phenols (-), flavonoids (-), phenylpropanoids (-) and others (-), are isolated from the plant. The mass spectrum cracking laws of representative compounds (, , , -, , , and ) are reviewed, which are conducive to the discovery of novel active substances. Modern pharmacological studies have shown that extracts and their compounds have antidiabetic, antidiabetic nephropathy, antioxidant, anti-inflammatory, antitumor, hepatoprotective, antiviral, antibacterial, immunopotentiation and other biological activities. The traditional uses, chemical constituents, compound cracking laws and pharmacological activities of different parts of are reviewed, laying the foundation for improving the development and utilization of its medicinal value.
（A. Juss.）Roem.，分布广泛，是药食同源植物资源。其叶、种子、树皮、芽和果皮均可入药，具有传统功效。由于其在古代传统医学中的广泛应用，该植物具有显著的发展潜力。在本综述中，从 植物中分离得到 206 种化合物，包括三萜类化合物（-）、倍半萜类化合物（-）、二萜类化合物（-）、甾体类化合物（-）、酚类化合物（-）、类黄酮类化合物（-）、苯丙素类化合物（-）和其他化合物（-）。综述了代表性化合物（、、、-、、、和）的质谱裂解规律，有利于发现新的活性物质。现代药理研究表明， 提取物及其化合物具有降血糖、防治糖尿病肾病、抗氧化、抗炎、抗肿瘤、保肝、抗病毒、抗菌、免疫增强等生物活性。对 不同部位的传统用途、化学成分、化合物裂解规律和药理活性进行了综述，为提高其药用价值的开发利用奠定了基础。
