Wason S
J Emerg Med. 1985;2(3):175-82. doi: 10.1016/0736-4679(85)90393-2.
Controversial therapeutic issues in patients with caustic ingestions concern the reliability of symptoms and signs in predicting esophageal injury, the appropriate use of endoscopy in evaluating esophageal damage, and the use of steroids in preventing late strictures. The conclusions of this review are: The majority of pediatric caustic ingestions involve a "lick and taste" whereas adolescents and adults often ingest substantial quantities. Oral burns and dysphagia are sensitive predictors of esophageal injury; however, esophageal injury may occur in the absence of the findings. Household bleach and nonphosphate detergents represent a low risk of injury whereas button batteries greater than 20 mm in diameter and Clinitest tablets represent high risk. Endoscopy should be an elective rather than emergency procedure and should be undertaken in all symptomatic patients, and in asymptomatic patients when history indicates substantial ingestion. Steroid therapy should be considered only for patients who have deep or circumferential esophageal burns.
腐蚀性物质摄入患者中存在争议的治疗问题涉及症状和体征在预测食管损伤方面的可靠性、内镜检查在评估食管损伤中的合理应用以及类固醇在预防晚期狭窄中的应用。本综述的结论如下:大多数儿童腐蚀性物质摄入属于“舔舐和品尝”,而青少年和成年人往往会大量摄入。口腔烧伤和吞咽困难是食管损伤的敏感预测指标;然而,即使没有这些表现也可能发生食管损伤。家用漂白剂和无磷洗涤剂造成损伤的风险较低,而直径大于20毫米的纽扣电池和葡萄糖氧化酶试纸条造成损伤的风险较高。内镜检查应是选择性而非急诊程序,所有有症状的患者以及病史表明有大量摄入的无症状患者均应进行内镜检查。仅应对有深部或环形食管烧伤的患者考虑使用类固醇治疗。