McGuigan M A
Ontario Regional Poison Information Centre, The Hospital for Sick Children, Toronto, Canada.
Paediatr Drugs. 1999 Oct-Dec;1(4):313-24. doi: 10.2165/00128072-199901040-00007.
Unintentional poisoning in children less than 6 years of age is a common occurrence. The majority of cases involve 1- and 2-year-old children who ingest nonpharmaceutical products. Although the clinical outcomes of these exposures is usually favourable, deaths do occur. In the US, the causes of death most commonly reported by the American Association of Poison Control Centers Toxic Exposure Surveillance System (AAPCC TESS) are carbon monoxide and adult formulations of iron. The exposures most commonly reported by the AAPCC TESS are cosmetic/personal care products (e.g. perfume, cologne and aftershave), household cleaning substances (e.g. bleach and alkaline corrosives) and analgesics [e.g. paracetamol (acetaminophen)]. Prevention is important and exposure to poisons should be considered a preventable childhood injury. The use of child-resistant packaging and the secure storage of household substances are the basis of preventing unintentional exposures. Parents and healthcare professionals need to be aware of what constitutes high risk exposure, as well as those exposures which are common but not serious. Poison prevention efforts should also address the appropriate role of the poison information centre.
6岁以下儿童意外中毒是常见现象。大多数病例涉及1至2岁的儿童,他们摄入了非药品类产品。尽管这些接触的临床结果通常良好,但确实会发生死亡。在美国,美国中毒控制中心协会毒物暴露监测系统(AAPCC TESS)最常报告的死亡原因是一氧化碳和成人用铁制剂。AAPCC TESS最常报告的接触物质是化妆品/个人护理产品(如香水、古龙水和须后水)、家用清洁用品(如漂白剂和碱性腐蚀剂)以及镇痛药[如对乙酰氨基酚(扑热息痛)]。预防很重要,接触毒物应被视为一种可预防的儿童伤害。使用儿童安全包装和妥善存放家用物品是预防意外接触的基础。家长和医护人员需要了解什么构成高风险接触,以及哪些接触常见但不严重。预防中毒的工作还应明确毒物信息中心的适当作用。