Vujovic Dragan, Alsen Mathilda, Vasan Vikram, Genden Eric, van Gerwen Maaike
Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Institute for Translational Epidemiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Cancers (Basel). 2024 Jan 26;16(3):545. doi: 10.3390/cancers16030545.
(1) Background: A pre-existing psychiatric condition may impact decision making by patients and/or physicians following a thyroid cancer diagnosis, such as potentially electing surgery over active surveillance, thus shortening the time to cancer removal. This is the first study to investigate the association between pre-existing anxiety and/or depression and time to receive surgical treatment for thyroid cancer. (2) Methods: Retrospective data were collected from 652 surgical thyroid cancer patients at our institution from 2018 to 2020. We investigated the time between thyroid cancer diagnosis and surgery, comparing patients with pre-existing anxiety and/or depression to those without. (3) Results: Patients with anxiety, depression, and both anxiety and depression had a significantly shorter time between diagnosis and surgery (51.6, 57, and 57.4 days, respectively) compared to patients without (111.9 days) ( = 0.002, = 0.004, = 0.003, respectively). (4) Conclusions: Although little is known about the impact of pre-existing psychiatric conditions in the decision-making process for thyroid cancer surgery, this present study showed that anxiety and/or depression may lead to more immediate surgical interventions. Thus, psychiatric history may be an important factor for physicians to consider when counseling patients with thyroid cancer.
(1) 背景：既往存在的精神疾病可能会影响甲状腺癌确诊后患者和/或医生的决策，例如可能选择手术而非主动监测，从而缩短癌症切除时间。这是第一项调查既往焦虑和/或抑郁与甲状腺癌接受手术治疗时间之间关联的研究。(2) 方法：收集了2018年至2020年我院652例甲状腺癌手术患者的回顾性数据。我们调查了甲状腺癌确诊与手术之间的时间，将有既往焦虑和/或抑郁的患者与没有的患者进行比较。(3) 结果：与没有焦虑、抑郁以及同时没有焦虑和抑郁的患者（111.9天）相比，有焦虑、抑郁以及同时有焦虑和抑郁的患者在确诊与手术之间的时间显著更短（分别为51.6天、57天和57.4天）（分别为P = 0.002、P = 0.004、P = 0.003）。(4) 结论：虽然对于既往精神疾病在甲状腺癌手术决策过程中的影响知之甚少，但本研究表明焦虑和/或抑郁可能导致更直接的手术干预。因此，精神病史可能是医生在为甲状腺癌患者提供咨询时需要考虑的一个重要因素。
