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现场经验教训:急性农药中毒的化合物特异性管理。

Lessons from the field: compound-specific management in acute pesticide poisoning.

机构信息

Pharmacology, Toxicology and Therapeutics, University/BHF Centre for Cardiovascular Science, University of Edinburgh, UK.

Department of Medicine, Chittagong Medical College and Hospital, Chattogram, Bangladesh.

出版信息

Trans R Soc Trop Med Hyg. 2024 Jun 4;118(6):347-349. doi: 10.1093/trstmh/trae003.

Abstract

Pesticide poisoning is a common medical emergency in the rural tropics, with significant associated mortality. Pesticide poisoning is an umbrella term that encompasses a wide variety of substances with differing clinical toxidromes and outcomes. Despite this, confirmation of the specific compound ingested is rarely performed. In this Lessons from the Field, we argue that pesticide-specific management is integral to optimise management. Using data from a quality improvement project in Chittagong, Bangladesh, we demonstrate that identifying the specific compound is possible in most patients through careful history taking and examination of the pesticide bottle. Identification of the specific compound is essential for anticipating and reducing complications, administering appropriate and timely management and reducing the length of hospital stay and cost of unnecessary medical intervention.

摘要

农药中毒是农村热带地区常见的急症,死亡率很高。农药中毒是一个广义的术语,包括多种具有不同临床中毒症状和结果的物质。尽管如此,很少对摄入的特定化合物进行确认。在本《实地教训》中,我们认为农药特异性管理是优化管理的关键。利用孟加拉国吉大港的一个质量改进项目的数据,我们证明通过仔细询问病史和检查农药瓶,大多数患者都可以确定具体的化合物。确定具体的化合物对于预测和减少并发症、给予适当和及时的治疗以及缩短住院时间和减少不必要的医疗干预的费用是至关重要的。

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本文引用的文献

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