Centre of Psychiatry Amager, Copenhagen University Hospital, Copenhagen, Denmark.
Faculty of Health Science, University of Faroe Islands, Torshavn, Faroe Islands.
Nord J Psychiatry. 2024 May;78(4):267-271. doi: 10.1080/08039488.2024.2315163. Epub 2024 Feb 10.
In an RCT study, OPAC (outreach, problem solving, adherence, continuity) approach to aftercare after suicide attempts had an effect. The present study used the OPAC method in a clinical setting on Amager Copenhagen to patients after suicide attempt (Group 1) and patients with suicide ideation (Group 2) in a real-world data (RWD) study.
To study whether the OPAC method could provide real world evidence (RWE) for results from the RCT study and long-time prospects.
This RWD study included 506 patients and followed them for 5 years. Kaplan-Meyer showed 5 years results. Risk factors for 5 years were calculated.
206 males (mean age 37.9) and 300 females (mean age 35.2) participated. A decline in survival accelerated after 3 years. After a 2-year follow-up, Group 1 had an attempted suicide rate of 12,2% and Group 2 5,4%. After 5 years the numbers were 18% and 10%. There were 3 completed suicides. Risk factors were: earlier suicide attempts, one or both parents or they themselves were alcohol/drug abusers, and a poor social network. Group 1 showed the same result as the intervention group in our earlier RCT study. Group 2 did better. Both groups did better than the control group from our RCT study.
The OPAC effect was translated into the daily clinic. Risk factors were previous suicide attempts, alcohol and drug abuse and poor social networks. More specific therapy is needed for some patients to prevent relapse. Focus on enhancing a sense of belongingness and/or treating substance abuse.
在一项 RCT 研究中,OPAC(外展、解决问题、依从性、连续性)方法对自杀未遂后的护理有效果。本研究在哥本哈根阿马格尔的临床环境中使用 OPAC 方法,对自杀未遂患者(第 1 组)和有自杀意念的患者(第 2 组)进行真实世界数据(RWD)研究。
研究 OPAC 方法是否能为 RCT 研究的结果和长期前景提供真实世界证据(RWE)。
这项 RWD 研究包括 506 名患者,并对他们进行了 5 年的随访。Kaplan-Meier 法显示了 5 年的结果。计算了 5 年的风险因素。
206 名男性(平均年龄 37.9)和 300 名女性(平均年龄 35.2)参与了研究。生存曲线在 3 年后加速下降。经过 2 年的随访,第 1 组的自杀未遂率为 12.2%,第 2 组为 5.4%。5 年后,这两组的数字分别为 18%和 10%。有 3 例自杀死亡。风险因素包括:以前的自杀企图、父母或自己是酒精/药物滥用者,以及社交网络较差。第 1 组的结果与我们之前的 RCT 研究中的干预组相同。第 2 组表现更好。与我们的 RCT 研究中的对照组相比,这两组都表现得更好。
OPAC 的效果转化为日常临床实践。风险因素包括以前的自杀尝试、酒精和药物滥用以及较差的社交网络。一些患者需要更具体的治疗以防止复发。重点是增强归属感和/或治疗物质滥用。