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感染性心内膜炎合并多发性脓毒性栓子:病例报告

An infective endocarditis complicated by multiple septic emboli: case report.

作者信息

Amri Meriam, Tamir El Mehdi, Drighil Abdenasser, Habbal Rachida

机构信息

Cardiology Department, CHU Ibn Rochd, Casablanca, Morocco.

出版信息

Egypt Heart J. 2024 Feb 10;76(1):19. doi: 10.1186/s43044-024-00451-z.

DOI:10.1186/s43044-024-00451-z
PMID:38340179
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10858854/
Abstract

BACKGROUND

Owing to challenges associated with heart failure and cardiac embolism, infectious endocarditis emerges as a critical pathology characterized by elevated mortality and morbidity rates. Our case stands out as a rare instance of endocarditis involving multisystem embolization, with a successful outcome.

CASE PRESENTATION

We present the case of an 81-year-old man whose admission was further complicated by various septic emboli affecting the brain (manifesting as a brain abscess and ischemic stroke), spleen (resulting in splenic infarction), and spinal cord. The patient received a diagnosis of infective endocarditis affecting the native mitral valve. Following prompt medical and surgical intervention, the overall progression was favorable despite encountering several challenges.

CONCLUSIONS

This case is notable for its detailed description and analysis of the multiple embolic events. More importantly, it underscores the significance of timely surgical intervention and the collaborative approach of a heart team in the face of complicated endocarditis marked by numerous septic emboli. Despite the typically grim prognosis associated with such cases, the outcomes emphasize the positive impact of timely surgery on prognosis.

摘要

背景

由于与心力衰竭和心脏栓塞相关的挑战,感染性心内膜炎成为一种以死亡率和发病率升高为特征的关键病理学疾病。我们的病例是罕见的涉及多系统栓塞的心内膜炎病例,且治疗成功。

病例介绍

我们报告一例81岁男性患者,其入院时因各种脓毒性栓子而病情更加复杂,这些栓子影响了大脑(表现为脑脓肿和缺血性中风)、脾脏(导致脾梗死)和脊髓。该患者被诊断为影响自身二尖瓣的感染性心内膜炎。经过及时的药物和手术干预,尽管遇到了一些挑战,但总体病情进展良好。

结论

本病例因其对多个栓塞事件的详细描述和分析而值得关注。更重要的是,它强调了及时进行手术干预以及心脏团队面对伴有大量脓毒性栓子的复杂性心内膜炎时采取协作方法的重要性。尽管此类病例通常预后不佳,但结果强调了及时手术对预后的积极影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c780/10858854/f9a42370dba3/43044_2024_451_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c780/10858854/eb38e81320c5/43044_2024_451_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c780/10858854/df780749dd9c/43044_2024_451_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c780/10858854/e5ebdc8b0f92/43044_2024_451_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c780/10858854/fb27f2001b96/43044_2024_451_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c780/10858854/f9a42370dba3/43044_2024_451_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c780/10858854/eb38e81320c5/43044_2024_451_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c780/10858854/df780749dd9c/43044_2024_451_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c780/10858854/e5ebdc8b0f92/43044_2024_451_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c780/10858854/fb27f2001b96/43044_2024_451_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c780/10858854/f9a42370dba3/43044_2024_451_Fig5_HTML.jpg

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